Molecules 2014, 19(4), 3898-3908; doi:10.3390/molecules19043898
Article

Further Mulinane and Azorellane Diterpenoids Isolated from Mulinum crassifolium and Azorella compacta

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Received: 3 March 2014; in revised form: 19 March 2014 / Accepted: 21 March 2014 / Published: 28 March 2014
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The new mulinane diterpenoids 1 and 2 were isolated from the EtOAc extract of Mulinum crassifolium, while the rearranged mulinane 5, which was isolated for the first time from a natural source, was isolated from Azorella compacta. Compounds 12 were prepared by semi-synthesis thorough acetylation of the diterpene 17-acetoxymulinic acid (3). A mechanism of reaction was proposed, while the structures of the new compounds were elucidated on the basis of comprehensive spectroscopic analysis and computational methods.
Keywords: mulinanes; azorellanes; new diterpenoids; Chilean native plants; semisynthesis
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MDPI and ACS Style

Bórquez, J.; Ardiles, A.; Loyola, L.A.; Peña-Rodriguez, L.M.; Molina-Salinas, G.M.; Vallejos, J.; Collado, I.G.; Simirgiotis, M.J. Further Mulinane and Azorellane Diterpenoids Isolated from Mulinum crassifolium and Azorella compacta. Molecules 2014, 19, 3898-3908.

AMA Style

Bórquez J, Ardiles A, Loyola LA, Peña-Rodriguez LM, Molina-Salinas GM, Vallejos J, Collado IG, Simirgiotis MJ. Further Mulinane and Azorellane Diterpenoids Isolated from Mulinum crassifolium and Azorella compacta. Molecules. 2014; 19(4):3898-3908.

Chicago/Turabian Style

Bórquez, Jorge; Ardiles, Alejandro; Loyola, Luis A.; Peña-Rodriguez, Luis M.; Molina-Salinas, Gloria M.; Vallejos, Javier; Collado, Isidro G.; Simirgiotis, Mario J. 2014. "Further Mulinane and Azorellane Diterpenoids Isolated from Mulinum crassifolium and Azorella compacta." Molecules 19, no. 4: 3898-3908.

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