Next Article in Journal
Comparison of Physicochemical Properties and Immunomodulatory Activity of Polysaccharides from Fresh and Dried Litchi Pulp
Previous Article in Journal
Structures of Two New Flavonoids and Effects of Licorice Phenolics on Vancomycin-Resistant Enterococcus Species
Molecules 2014, 19(4), 3898-3908; doi:10.3390/molecules19043898
Article

Further Mulinane and Azorellane Diterpenoids Isolated from Mulinum crassifolium and Azorella compacta

1
,
1,6
,
1
,
2
,
3,4
,
5
,
6
 and
1,*
Received: 3 March 2014 / Revised: 19 March 2014 / Accepted: 21 March 2014 / Published: 28 March 2014
View Full-Text   |   Download PDF [873 KB, uploaded 18 June 2014]   |   Browse Figures

Abstract

The new mulinane diterpenoids 1 and 2 were isolated from the EtOAc extract of Mulinum crassifolium, while the rearranged mulinane 5, which was isolated for the first time from a natural source, was isolated from Azorella compacta. Compounds 12 were prepared by semi-synthesis thorough acetylation of the diterpene 17-acetoxymulinic acid (3). A mechanism of reaction was proposed, while the structures of the new compounds were elucidated on the basis of comprehensive spectroscopic analysis and computational methods.
Keywords: mulinanes; azorellanes; new diterpenoids; Chilean native plants; semisynthesis mulinanes; azorellanes; new diterpenoids; Chilean native plants; semisynthesis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplement

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Bórquez, J.; Ardiles, A.; Loyola, L.A.; Peña-Rodriguez, L.M.; Molina-Salinas, G.M.; Vallejos, J.; Collado, I.G.; Simirgiotis, M.J. Further Mulinane and Azorellane Diterpenoids Isolated from Mulinum crassifolium and Azorella compacta. Molecules 2014, 19, 3898-3908.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

Cited By

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert