Molecules 2014, 19(3), 2808-2818; doi:10.3390/molecules19032808
Article

Inhibitory Effect of Corn Silk on Skin Pigmentation

1,2,* email, 1email, 1email, 1email, 3email, 4email and 4email
Received: 27 December 2013; in revised form: 21 February 2014 / Accepted: 25 February 2014 / Published: 3 March 2014
(This article belongs to the Section Natural Products)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: In this study, the inhibitory effect of corn silk on melanin production was evaluated. This study was performed to investigate the inhibitory effect of corn silk on melanin production in Melan-A cells by measuring melanin production and protein expression. The corn silk extract applied on Melan-A cells at a concentration of 100 ppm decreased melanin production by 37.2% without cytotoxicity. This was a better result than arbutin, a positive whitening agent, which exhibited a 26.8% melanin production inhibitory effect at the same concentration. The corn silk extract did not suppress tyrosinase activity but greatly reduced the expression of tyrosinase in Melan-A cells. In addition, corn silk extract was applied to the human face with hyperpigmentation, and skin color was measured to examine the degree of skin pigment reduction. The application of corn silk extract on faces with hyperpigmentation significantly reduced skin pigmentation without abnormal reactions. Based on the results above, corn silk has good prospects for use as a material for suppressing skin pigmentation.
Keywords: corn silk; melanin; skin; tyrosinase
PDF Full-text Download PDF Full-Text [737 KB, uploaded 18 June 2014 20:32 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Choi, S.Y.; Lee, Y.; Kim, S.S.; Ju, H.M.; Baek, J.H.; Park, C.-S.; Lee, D.-H. Inhibitory Effect of Corn Silk on Skin Pigmentation. Molecules 2014, 19, 2808-2818.

AMA Style

Choi SY, Lee Y, Kim SS, Ju HM, Baek JH, Park C-S, Lee D-H. Inhibitory Effect of Corn Silk on Skin Pigmentation. Molecules. 2014; 19(3):2808-2818.

Chicago/Turabian Style

Choi, Sang Y.; Lee, Yeonmi; Kim, Sung S.; Ju, Hyun M.; Baek, Ji H.; Park, Chul-Soo; Lee, Dong-Hyuk. 2014. "Inhibitory Effect of Corn Silk on Skin Pigmentation." Molecules 19, no. 3: 2808-2818.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert