Next Article in Journal
New Thiophene and Flavonoid from Tagetes minuta Leaves Growing in Saudi Arabia
Previous Article in Journal
Astragalus membranaceus Improves Exercise Performance and Ameliorates Exercise-Induced Fatigue in Trained Mice
Article Menu

Export Article

Open AccessArticle
Molecules 2014, 19(3), 2808-2818; doi:10.3390/molecules19032808

Inhibitory Effect of Corn Silk on Skin Pigmentation

Korea Food Research Institute, Seongnam 463-746, Korea
Department of Food Biotechnology, University of Science and Technology (UST), Daejeon 305-350, Korea
Dermapro Co. Ltd., Seoul 156-709, Korea
Kwang-Dong Pharmaceutical Co. Ltd, Seoul 137-875, Korea
Author to whom correspondence should be addressed.
Received: 27 December 2013 / Revised: 21 February 2014 / Accepted: 25 February 2014 / Published: 3 March 2014
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [737 KB, uploaded 18 June 2014]   |  


In this study, the inhibitory effect of corn silk on melanin production was evaluated. This study was performed to investigate the inhibitory effect of corn silk on melanin production in Melan-A cells by measuring melanin production and protein expression. The corn silk extract applied on Melan-A cells at a concentration of 100 ppm decreased melanin production by 37.2% without cytotoxicity. This was a better result than arbutin, a positive whitening agent, which exhibited a 26.8% melanin production inhibitory effect at the same concentration. The corn silk extract did not suppress tyrosinase activity but greatly reduced the expression of tyrosinase in Melan-A cells. In addition, corn silk extract was applied to the human face with hyperpigmentation, and skin color was measured to examine the degree of skin pigment reduction. The application of corn silk extract on faces with hyperpigmentation significantly reduced skin pigmentation without abnormal reactions. Based on the results above, corn silk has good prospects for use as a material for suppressing skin pigmentation.
Keywords: corn silk; melanin; skin; tyrosinase corn silk; melanin; skin; tyrosinase
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Choi, S.Y.; Lee, Y.; Kim, S.S.; Ju, H.M.; Baek, J.H.; Park, C.-S.; Lee, D.-H. Inhibitory Effect of Corn Silk on Skin Pigmentation. Molecules 2014, 19, 2808-2818.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top