New Thiophene and Flavonoid from Tagetes minuta Leaves Growing in Saudi Arabia
AbstractPhytochemical investigation of the methanolic extract of Tagetes minuta L. (Asteraceae) leaves resulted in the isolation and identification of two new compounds: 5-methyl-2,2',5',2'',5'',2''',5''',2''''-quinquethiophene (1) and quercetagetin-6-O-(6-O-caffeoyl-β-D-glucopyranoside) (9), in addition to seven known compounds: quercetin-3,6-dimethyl ether (2), quercetin-3-methyl ether (3), quercetin (4), axillarin-7-O-β-D-glucopyranoside (5), quercetagetin-3,7-dimethoxy-6-O-β-D-glucopyranoside (6), quercetagetin-7-methoxy-6-O-β-D-glucopyranoside (7), and quercetagetin-6-O-β-D-glucopyranoside (8). The compounds were identified by UV, IR, 1D, 2D NMR, and HRESIMS spectral data. They showed significant antioxidant activity, comparable with that of propyl gallate. Compounds 8 and 3 showed weak to moderate antileishmanial and antimalarial activities, with IC50 values of 31.0 μg/mL and 4.37 μg/mL, respectively.
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Al-Musayeib, N.M.; Mohamed, G.A.; Ibrahim, S.R.M.; Ross, S.A. New Thiophene and Flavonoid from Tagetes minuta Leaves Growing in Saudi Arabia. Molecules 2014, 19, 2819-2828.
Al-Musayeib NM, Mohamed GA, Ibrahim SRM, Ross SA. New Thiophene and Flavonoid from Tagetes minuta Leaves Growing in Saudi Arabia. Molecules. 2014; 19(3):2819-2828.Chicago/Turabian Style
Al-Musayeib, Nawal M.; Mohamed, Gamal A.; Ibrahim, Sabrin R.M.; Ross, Samir A. 2014. "New Thiophene and Flavonoid from Tagetes minuta Leaves Growing in Saudi Arabia." Molecules 19, no. 3: 2819-2828.