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Molecules 2014, 19(1), 1178-1188; doi:10.3390/molecules19011178

A New Sesquilignan Glucoside from Uraria sinensis

1, 1, 1, 1, 1, 2,*  and 1,*
1 Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China 2 First College of Clinical Medical Science of China, Three Gorges University & Yichang Central People's Hospital, Yichang 443003, China
* Authors to whom correspondence should be addressed.
Received: 26 November 2013 / Revised: 7 January 2014 / Accepted: 13 January 2014 / Published: 17 January 2014
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A new sesquilignan glucoside, urariasinoside A (1), together with eight known compounds, including two lignans, a sesquilignan, a dilignan, and four flavonoid derivatives were isolated from the aerial parts of Uraria sinensis. Their structures were determined on the basis of extensive spectroscopic analyses and comparison with literature data. Compound 1 was evaluated for in vitro cytotoxicity activity against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines.
Keywords: Uraria sinensis; sesquilignan glucoside; lignans; flavonoids Uraria sinensis; sesquilignan glucoside; lignans; flavonoids
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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Yang, Y.; Hu, Z.; Luo, Z.; Xue, Y.; Yao, G.; Wang, Y.; Zhang, Y. A New Sesquilignan Glucoside from Uraria sinensis. Molecules 2014, 19, 1178-1188.

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