Molecules 2013, 18(5), 4917-4928; doi:10.3390/molecules18054917
Article

A Preliminary Study of the Effect of DBD Plasma and Osmolytes on T98G Brain Cancer and HEK Non-Malignant Cells

Plasma Bioscience Research Center, Kwangwoon University, Seoul 139701, Korea
* Authors to whom correspondence should be addressed.
Received: 16 February 2013; in revised form: 11 April 2013 / Accepted: 23 April 2013 / Published: 25 April 2013
(This article belongs to the Section Medicinal Chemistry)
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Abstract: Non-thermal plasmas are emerging as a novel tool for the treatment of living tissues for biological and medical purpose. In this study, we described the effect of 4 min dielectric barrier discharge (DBD) plasma on both T98G cancer and HEK normal cell lines in the presence of different concentrations of osmolytes. This treatment strategy shows a specific inhibitory effect of a 240 s plasma exposure in the presence of osmolytes against T98G brain cancer cells only, but not on HEK normal cells. Based on these interesting properties of osmolytes, a non-thermal plasma appears to be a potential anticancer treatment strategy for different kinds of cancers in the presence of osmolytes.
Keywords: osmolytes; plasma; brain cancer cells; non-malignant cells

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MDPI and ACS Style

Kaushik, N.K.; Attri, P.; Kaushik, N.; Choi, E.H. A Preliminary Study of the Effect of DBD Plasma and Osmolytes on T98G Brain Cancer and HEK Non-Malignant Cells. Molecules 2013, 18, 4917-4928.

AMA Style

Kaushik NK, Attri P, Kaushik N, Choi EH. A Preliminary Study of the Effect of DBD Plasma and Osmolytes on T98G Brain Cancer and HEK Non-Malignant Cells. Molecules. 2013; 18(5):4917-4928.

Chicago/Turabian Style

Kaushik, Nagendra K.; Attri, Pankaj; Kaushik, Neha; Choi, Eun H. 2013. "A Preliminary Study of the Effect of DBD Plasma and Osmolytes on T98G Brain Cancer and HEK Non-Malignant Cells." Molecules 18, no. 5: 4917-4928.

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