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Molecules 2013, 18(4), 3962-3971; doi:10.3390/molecules18043962

Macrocyclic Spermidine Alkaloids from Androya decaryi L. Perrier

1,* , 1, 2, 3, 1, 1, 1 and 1
1 Université de Toulouse; UMR 152 UPS-IRD (Pharmacochimie et Pharmacologie pour le Développement-PHARMA DEV), F-31062 Toulouse Cedex 9, France 2 Laboratoire de Chimie de la Faculté des Sciences, Université de Toliara, BP 185 Maninday Toliara 602, Madagascar 3 Institut de Chimie de Toulouse, Université de Toulouse, UPS, FR2599, 118 route de Narbonne, F-31062 Toulouse Cedex 9, France
* Author to whom correspondence should be addressed.
Received: 18 February 2013 / Revised: 28 March 2013 / Accepted: 29 March 2013 / Published: 4 April 2013
(This article belongs to the Section Natural Products)
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Three new spermidine alkaloids and two known compounds were isolated from the leaves of Androya decaryi. Their structures were elucidated on the basis of their spectroscopic data (NMR and mass spectrometry), by X-Ray diffraction and by comparison with literature values. Evaluation of the in vitro antiplamosdial properties of the isolated compounds revealed they did not possess any significant activity.
Keywords: Androya; Scrophulariaceae; spermidine alkaloids Androya; Scrophulariaceae; spermidine alkaloids
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Le Lamer, A.-C.; Ibrahim, N.; Manjary, F.; Mallet-Ladeira, S.; Girardi, C.; Valentin, A.; Fabre, N.; Moulis, C. Macrocyclic Spermidine Alkaloids from Androya decaryi L. Perrier. Molecules 2013, 18, 3962-3971.

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