Molecules 2013, 18(11), 13435-13445; doi:10.3390/molecules181113435
Article

Polyphenolic Extracts of Edible Flowers Incorporated onto Atelocollagen Matrices and Their Effect on Cell Viability

1email, 1,2email, 1,2,* email, 3email and 1email
Received: 30 August 2013; in revised form: 3 October 2013 / Accepted: 23 October 2013 / Published: 30 October 2013
(This article belongs to the Section Natural Products)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The phenolic extract of chives flowers (Allium schoenoprasum, Liliaceae), introduced Sage (Salvia pratensis, Lamiaceae), European elderberry (Sambucus nigra, Caprifoliaceae) and common dandelion (Taraxacum officinale, Asteraceae) were characterised by High Performance Liquid Chromatography and incorporated in different concentrations onto atelocollagen thin films. In order to assess the biological impact of these phenolic compounds on cell viability, human immortalised non-tumorigenic keratinocyte cell line was seeded on the thin films and cell proliferation was determined by using an MTT assay. In addition, their antimicrobial activity was estimated by using an agar diffusion test. Data indicated the concomitance between cell viability and concentration of polyphenols. These findings suggest that these phenolic-endowed atelocollagen films might be suitable for tissue engineering applications, on account of the combined activity of polyphenols and collagen.
Keywords: edible flowers; polyphenolic extracts; atelocollagen thin films; cell viability; tissue engineering
PDF Full-text Download PDF Full-Text [801 KB, uploaded 18 June 2014 20:14 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

López-García, J.; Kuceková, Z.; Humpolíček, P.; Mlček, J.; Sáha, P. Polyphenolic Extracts of Edible Flowers Incorporated onto Atelocollagen Matrices and Their Effect on Cell Viability. Molecules 2013, 18, 13435-13445.

AMA Style

López-García J, Kuceková Z, Humpolíček P, Mlček J, Sáha P. Polyphenolic Extracts of Edible Flowers Incorporated onto Atelocollagen Matrices and Their Effect on Cell Viability. Molecules. 2013; 18(11):13435-13445.

Chicago/Turabian Style

López-García, Jorge; Kuceková, Zdenka; Humpolíček, Petr; Mlček, Jiři; Sáha, Petr. 2013. "Polyphenolic Extracts of Edible Flowers Incorporated onto Atelocollagen Matrices and Their Effect on Cell Viability." Molecules 18, no. 11: 13435-13445.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert