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Molecules 2013, 18(10), 11859-11865; doi:10.3390/molecules181011859

Chemical Constituents from the Roots of Ranunculus ternatus and their Inhibitory Effects on Mycobacterium tuberculosis

Beijing University of Chinese Medicine, Beijing 100029, China
Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
Jiangxi Science and Technology Normal University, Nanchang 330038, China
Authors to whom correspondence should be addressed.
Received: 12 August 2013 / Revised: 14 September 2013 / Accepted: 17 September 2013 / Published: 25 September 2013
(This article belongs to the Section Natural Products)
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Two new benzophenones, methyl (R)-3-[2-(3,4-dihydroxybenzoyl)-4,5-dihydroxyphenyl]-2-hydroxypropanoate (1) and n-butyl (R)-3-[2-(3,4-dihydroxybenzoyl)-4,5-dihydroxyphenyl]-2-hydroxypropanoate (2), were isolated from the roots of Ranunculus ternatus along with the two known compounds vanillic acid (3) and gallic acid (4). Their structures were elucidated by physical and spectroscopic analysis. In addition, compound 1 exhibited obvious activity against tuberculosis, while the activity of a 1:1 mixture of compound 1 plus 4 is better than that of 1 alone.
Keywords: Ranunculus ternatus; benzophenones; tuberculosis Ranunculus ternatus; benzophenones; tuberculosis
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Deng, K.-Z.; Xiong, Y.; Zhou, B.; Guan, Y.-M.; Luo, Y.-M. Chemical Constituents from the Roots of Ranunculus ternatus and their Inhibitory Effects on Mycobacterium tuberculosis. Molecules 2013, 18, 11859-11865.

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