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Molecules 2013, 18(1), 190-203; doi:10.3390/molecules18010190

Article

Synthesis and Characterization of Carboxymethyl Chitosan Nanogels for Swelling Studies and Antimicrobial Activity

Reem K. Farag ¹  and Riham R. Mohamed ^2,*

¹ Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, 11727, Egypt ² Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt

* Author to whom correspondence should be addressed.

Received: 12 October 2012; in revised form: 13 December 2012 / Accepted: 18 December 2012 / Published: 24 December 2012

Download PDF Full-Text [714 KB, Updated Version, uploaded 31 December 2012 11:19 CET]

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Abstract: Nanogels of a binary system of carboxymethyl chitosan (CMCh) and poly- (vinyl alcohol) PVA, were successfully synthesized by a novel in situ process. They were also characterized by various analytical tools like Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and X-ray diffraction (XRD). They were studied for their unique swelling properties in water and different pH solutions. They were also investigated for their great ability to capture or isolate bacteria and fungi from aquatic environments.

Keywords: carboxymethyl chitosan; poly(vinyl alcohol); nanogels; antimicrobial activity; swelling ability

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