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Molecules 2012, 17(9), 10192-10231; doi:10.3390/molecules170910192
Review

Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles: A Review of the Literature from 2000–2012

1
,
1
,
2
,
2
 and
1,*
1 Department of Chemistry, Federal University of Paraíba, 58051-900 João Pessoa-PB, Brazil 2 Laboratory of Pharmaceutical Technology, Federal University of Paraíba, 58051-900 João Pessoa-PB, Brazil
* Author to whom correspondence should be addressed.
Received: 23 July 2012 / Revised: 15 August 2012 / Accepted: 17 August 2012 / Published: 27 August 2012
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Abstract

This review provides readers with an overview of the main synthetic methodologies for 1,3,4-oxadiazole derivatives, and of their broad spectrum of pharmacological activities as reported over the past twelve years.
Keywords: 1,3,4-oxadiazole; synthesis methods; pharmacological activity; review 1,3,4-oxadiazole; synthesis methods; pharmacological activity; review
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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de Oliveira, C.S.; Lira, B.F.; Barbosa-Filho, J.M.; Lorenzo, J.G.F.; de Athayde-Filho, P.F. Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles: A Review of the Literature from 2000–2012. Molecules 2012, 17, 10192-10231.

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