Molecules 2012, 17(8), 9931-9938; doi:10.3390/molecules17089931
Article

The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside

1,* email, 2, 1, 1, 3, 1, 1 and 2
Received: 12 June 2012; in revised form: 7 August 2012 / Accepted: 8 August 2012 / Published: 17 August 2012
(This article belongs to the Section Metabolites)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Through bioassay-guided isolation, five compounds with growth inhibitory activity on S1T, an adult T-cell leukemia (ATL) cell line, were isolated from the crude methanol extract of the aerial parts of Hyptis verticillata.
Keywords: ATL; bioassay-guided isolation; S1T; growth inhibitor; lignan; NMR; structure
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MDPI and ACS Style

Hamada, T.; White, Y.; Nakashima, M.; Oiso, Y.; Fujita, M.J.; Okamura, H.; Iwagawa, T.; Arima, N. The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside. Molecules 2012, 17, 9931-9938.

AMA Style

Hamada T, White Y, Nakashima M, Oiso Y, Fujita MJ, Okamura H, Iwagawa T, Arima N. The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside. Molecules. 2012; 17(8):9931-9938.

Chicago/Turabian Style

Hamada, Toshiyuki; White, Yohann; Nakashima, Mitsuyoshi; Oiso, Yusuke; Fujita, Masaki J.; Okamura, Hiroaki; Iwagawa, Tetsuo; Arima, Naomichi. 2012. "The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside." Molecules 17, no. 8: 9931-9938.


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