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Molecules 2012, 17(8), 9835-9841; doi:10.3390/molecules17089835

Towards Recyclable NAD(P)H Regeneration Catalysts

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Received: 14 June 2012 / Revised: 1 August 2012 / Accepted: 8 August 2012 / Published: 15 August 2012
(This article belongs to the Special Issue Enzyme-Catalyzed Reactions)
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Abstract: Rh(III)-TsDPEN, an immobilized analog of the well-known [Cp*Rh(bpy)(H2O)]2+ was evaluated as a heterogeneous, recyclable regeneration catalyst for reduced oxidoreductase cofactors [NAD(P)H]. Repeated use of this catalyst was established and the catalytic properties were initially investigated. Apparently, Rh(III)-TsDPEN is prone to severe diffusion limitations, necessitating further developments. Overall, a promising concept for chemoenzymatic redox catalysis is proposed, which may overcome some of the current limitations such as catalyst cost and incompatibility of Rh with some biocatalysts.
Keywords: biocatalysis; cofactor regeneration; chemoenzymatic cascades; immobilized catalysts biocatalysis; cofactor regeneration; chemoenzymatic cascades; immobilized catalysts
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

de Torres, M.; Dimroth, J.; Arends, I.W.C.E.; Keilitz, J.; Hollmann, F. Towards Recyclable NAD(P)H Regeneration Catalysts. Molecules 2012, 17, 9835-9841.

AMA Style

de Torres M, Dimroth J, Arends IWCE, Keilitz J, Hollmann F. Towards Recyclable NAD(P)H Regeneration Catalysts. Molecules. 2012; 17(8):9835-9841.

Chicago/Turabian Style

de Torres, Miriam; Dimroth, Jonas; Arends, Isabel W. C. E.; Keilitz, Juliane; Hollmann, Frank. 2012. "Towards Recyclable NAD(P)H Regeneration Catalysts." Molecules 17, no. 8: 9835-9841.

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