Molecules 2012, 17(8), 9716-9727; doi:10.3390/molecules17089716

Diterpenoids from the Buds of Pinus banksiana Lamb.

email, email, email, email and * email
Received: 12 June 2012; in revised form: 5 August 2012 / Accepted: 10 August 2012 / Published: 13 August 2012
(This article belongs to the Section Metabolites)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Three new diterpenoids, namely 7α-hydroxyabieta-8,11,13,15-tetraen-18-oic acid, 7β,15,18-trihydroxyabieta-8,11,13-triene, 13,15-dihydroxypodocarpa-8,11,13-triene, and 12 other known compounds were isolated from buds of Pinus banksiana Lamb. All these compounds, except for 7-oxodehydroabietinol, were isolated for the first time from this plant. Their structures were elucidated by detailed spectroscopic studies and comparison with published data. All isolated compounds were tested for cytotoxic and antibacterial activities. Overall, two compounds, 7-oxodehydroabietinol and 18-nor-4,15-dihydroxyabieta-8,11,13-trien-7-one, showed moderate cytotoxicity against a human lung carcinoma cell line.
Keywords: Pinus banksiana; bud; dehydroabietane; cytotoxicity; antibacterial activity
PDF Full-text Download PDF Full-Text [257 KB, uploaded 18 June 2014 19:52 CEST]

Export to BibTeX |

MDPI and ACS Style

Georges, P.; Legault, J.; Lavoie, S.; Grenon, C.; Pichette, A. Diterpenoids from the Buds of Pinus banksiana Lamb.. Molecules 2012, 17, 9716-9727.

AMA Style

Georges P, Legault J, Lavoie S, Grenon C, Pichette A. Diterpenoids from the Buds of Pinus banksiana Lamb.. Molecules. 2012; 17(8):9716-9727.

Chicago/Turabian Style

Georges, Patricia; Legault, Jean; Lavoie, Serge; Grenon, Carole; Pichette, André. 2012. "Diterpenoids from the Buds of Pinus banksiana Lamb.." Molecules 17, no. 8: 9716-9727.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert