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Molecules 2012, 17(8), 8872-8885; doi:10.3390/molecules17088872
Article

Screening and Analysis of the Potential Bioactive Components in Rabbit Plasma after Oral Administration of Hot-Water Extracts from Leaves of Bambusa textilis McClure

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Received: 8 June 2012; in revised form: 17 July 2012 / Accepted: 18 July 2012 / Published: 26 July 2012
(This article belongs to the Section Metabolites)
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Abstract: Bambusa textilis McClure is a traditional Chinese medicinal plant belonging to the Bambusoideae subfamily and used to treat chronic fever and infectious diseases. To investigate the bioactive compounds absorbed in the rabbit blood after oral administration of hot-water extracts from the leaves of B. textilis McClure, a validated chromatographic fingerprint method was established using LC-Q-TOF-MS. Twenty compounds in bamboo leaves and three potential bioactive compounds in rabbit plasma were detected. Of the twenty detected compounds in vitro, fifteen of which were tentatively identified either by comparing the retention time and mass spectrometry data with that of reference compounds or by reviewing the literature. Three potential bioactive compounds, including (E)-p-coumaric acid, (Z)-p-coumaric acid, and apigenin-8-C-β-D-(2"-O-α-L-rhamnosyl)-gluco-pyranoside, were detected in both the leaves of B. textilis McClure and rabbit plasma. Of the three compounds, apigenin-8-C-β-D-(2"-O-α-L-rhamnosyl)glucopyranoside was identified based on its UV, MS, and NMR spectra. This study provides helpful chemical information for further pharmacology and active mechanism research on B. textilis McClure.
Keywords: Bambusa textilis McClure; LC-Q-TOF-MS; chemical fingerprint; bioactive compounds in rabbit plasma; structure elucidation Bambusa textilis McClure; LC-Q-TOF-MS; chemical fingerprint; bioactive compounds in rabbit plasma; structure elucidation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Wang, J.; Yue, Y.-D.; Tang, F.; Sun, J. Screening and Analysis of the Potential Bioactive Components in Rabbit Plasma after Oral Administration of Hot-Water Extracts from Leaves of Bambusa textilis McClure. Molecules 2012, 17, 8872-8885.

AMA Style

Wang J, Yue Y-D, Tang F, Sun J. Screening and Analysis of the Potential Bioactive Components in Rabbit Plasma after Oral Administration of Hot-Water Extracts from Leaves of Bambusa textilis McClure. Molecules. 2012; 17(8):8872-8885.

Chicago/Turabian Style

Wang, Jin; Yue, Yong-De; Tang, Feng; Sun, Jia. 2012. "Screening and Analysis of the Potential Bioactive Components in Rabbit Plasma after Oral Administration of Hot-Water Extracts from Leaves of Bambusa textilis McClure." Molecules 17, no. 8: 8872-8885.


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