Next Article in Journal
Terpene Glycosides from the Roots of Sanguisorba officinalis L. and Their Hemostatic Activities
Previous Article in Journal
Down Regulation of CIAPIN1 Reverses Multidrug Resistance in Human Breast Cancer Cells by Inhibiting MDR1
Molecules 2012, 17(7), 7612-7628; doi:10.3390/molecules17077612
Review

Thiadiazines, N,N-Heterocycles of Biological Relevance

1,* , 2
 and
1,3,4,*
Received: 7 May 2012 / Revised: 16 June 2012 / Accepted: 19 June 2012 / Published: 25 June 2012
Download PDF [412 KB, uploaded 18 June 2014]

Abstract

The 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione scaffold has found many applications in recent years. This review is aimed at highlighting the most important aspects of these compounds: Synthesis, spectroscopic characterization and biological activities. How the chemical nature of N-substituents influences the overall activity and cytotoxicity profile will also be discussed.
Keywords: heterocycles; thiadiazines; synthesis and biological activity heterocycles; thiadiazines; synthesis and biological activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Rodríguez, H.; Suárez, M.; Albericio, F. Thiadiazines, N,N-Heterocycles of Biological Relevance. Molecules 2012, 17, 7612-7628.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

Cited By

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert