Next Article in Journal
Phaeophytin Analogues from Ligularia knorringiana
Previous Article in Journal
Impact of Elevated Carbon Dioxide on Primary, Secondary Metabolites and Antioxidant Responses of Eleais guineensis Jacq. (Oil Palm) Seedlings
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2012, 17(5), 5212-5218; doi:10.3390/molecules17055212

Benzyl 2-β-Glucopyranosyloxybenzoate, a New Phenolic Acid Glycoside from Sarcandra glabra

1
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China
2
National Institutes for Food and Drug Control, Beijing 100050, China
*
Author to whom correspondence should be addressed.
Received: 13 April 2012 / Revised: 23 April 2012 / Accepted: 23 April 2012 / Published: 4 May 2012
(This article belongs to the Section Natural Products)
Download PDF [264 KB, uploaded 18 June 2014]

Abstract

From the whole plant of Sarcandra glabra, a new phenolic acid glycoside, benzyl 2-β-glucopyranosyloxybenzoate (1), together with seven known compounds including eleutheroside B1 (2), 5-O-caffeoylshikimic acid (3), (–)-(7S, 8R)-dihydrodehydro-diconiferyl alcohol (4), (–)-(7S, 8R)-dihydrodehydrodiconiferyl alcohol 9-, 9′- and 4-O-â-D-glucopyranoside (57), and (–)-(7S, 8R)-5-methoxydihydrodehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside (8) was isolated. Their structures were elucidated by spectral analysis including 1D-, 2D-NMR and HR-ESI-MS. Compound 2 was found to exhibit potent cytotoxic activity against BGC-823 and A2780 cancer cell lines using MTT method with IC50 value of 2.53 and 1.85 µM, respectively.
Keywords: Sarcandra glabra; chloranthaceae; benzyl 2-β-D-glucopyranosyloxybenzoate; anticancer activity Sarcandra glabra; chloranthaceae; benzyl 2-β-D-glucopyranosyloxybenzoate; anticancer activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Wu, H.; Hu, X.; Zhang, X.; Chen, S.; Yang, J.; Xu, X. Benzyl 2-β-Glucopyranosyloxybenzoate, a New Phenolic Acid Glycoside from Sarcandra glabra. Molecules 2012, 17, 5212-5218.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top