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Molecules 2012, 17(5), 5219-5224; doi:10.3390/molecules17055219
Article

Phaeophytin Analogues from Ligularia knorringiana

1
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1
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1,*
Received: 15 March 2012 / Revised: 25 April 2012 / Accepted: 27 April 2012 / Published: 7 May 2012
(This article belongs to the Section Metabolites)
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Abstract

A new phaeophytin, ligulariaphytin A, together with five known phaeophytins, were isolated from the aerial parts of Ligularia knorringiana. The structure of ligulariaphytin A was elucidated as 131-hydroxy-131,132-peroxyphaeophorbide A ethyl ester (1), and the five known compounds were identified as 132-hydroxyphaeophorbide A ethyl ester (2), 173-ethoxyphaeophorbide A (3), phaeophytin B (4), phaeophytin A (5), and phaeophorbide B ethyl ester (6), respectively, based on spectroscopic analysis and by comparison of their spectral data with those reported previously in the literature. All compounds were evaluated for their in vitro cytotoxic activities against cultured Hela cell, and were found to show only very weak cytotoxicity.
Keywords: Ligularia knorringiana; phaeophytins; ligulariaphytin A Ligularia knorringiana; phaeophytins; ligulariaphytin A
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Li, H.; Li, L.; Zheng, Q.; Kuroda, C.; Wang, Q. Phaeophytin Analogues from Ligularia knorringiana. Molecules 2012, 17, 5219-5224.

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