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Molecules 2012, 17(3), 2812-2822; doi:10.3390/molecules17032812
Communication

Efficient Synthesis of β-Enaminones and β-Enaminoesters Catalyzed by Gold (I)/Silver (I) under Solvent-Free Conditions

1
, 1,2
, 1
 and 1,3,*
1 State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China 2 School of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China 3 State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
* Author to whom correspondence should be addressed.
Received: 15 January 2012 / Revised: 16 February 2012 / Accepted: 17 February 2012 / Published: 6 March 2012
(This article belongs to the Section Organic Synthesis)
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Abstract

An efficient method for the synthesis of β-enaminones and β-enaminoesters using a combination of [(PPh3)AuCl]/AgOTf as catalyst has been developed. The reaction between 1,3-dicarbonyl compounds and primary amines was carried out under solvent-free conditions with low catalyst loading in good to excellent yields at room temperature.
Keywords: gold; solvent-free; amines; β-enaminones; β-enaminoesters gold; solvent-free; amines; β-enaminones; β-enaminoesters
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Zhang, M.; Abdukader, A.; Fu, Y.; Zhu, C. Efficient Synthesis of β-Enaminones and β-Enaminoesters Catalyzed by Gold (I)/Silver (I) under Solvent-Free Conditions. Molecules 2012, 17, 2812-2822.

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