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Molecules 2012, 17(3), 2675-2682; doi:10.3390/molecules17032675
Article

Bioactive Phenolic Amides from Celtis africana

1, 1,* , 1, 1,2, 3, 4, 4 and 4
Received: 4 January 2012; in revised form: 20 February 2012 / Accepted: 27 February 2012 / Published: 5 March 2012
(This article belongs to the Section Metabolites)
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Abstract: Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were screened for their antioxidant, anti-inflammatory and acetylcholinestrease enzyme inhibitory activities. Compounds 13 showed significant antioxidant and anti-inflammatory activities and weak to moderate acetylcholinestrease enzyme inhibition activity.
Keywords: Celtis africana; antioxidant; anti-inflammatory; acetylcholinestrease enzyme inhibition Celtis africana; antioxidant; anti-inflammatory; acetylcholinestrease enzyme inhibition
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Al-Taweel, A.M.; Perveen, S.; El-Shafae, A.M.; Fawzy, G.A.; Malik, A.; Afza, N.; Iqbal, L.; Latif, M. Bioactive Phenolic Amides from Celtis africana. Molecules 2012, 17, 2675-2682.

AMA Style

Al-Taweel AM, Perveen S, El-Shafae AM, Fawzy GA, Malik A, Afza N, Iqbal L, Latif M. Bioactive Phenolic Amides from Celtis africana. Molecules. 2012; 17(3):2675-2682.

Chicago/Turabian Style

Al-Taweel, Areej Mohammad; Perveen, Shagufta; El-Shafae, Azza Muhammed; Fawzy, Ghada Ahmed; Malik, Abdul; Afza, Nighat; Iqbal, Lubna; Latif, Mehreen. 2012. "Bioactive Phenolic Amides from Celtis africana." Molecules 17, no. 3: 2675-2682.


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