Abstract: Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were screened for their antioxidant, anti-inflammatory and acetylcholinestrease enzyme inhibitory activities. Compounds 1–3 showed significant antioxidant and anti-inflammatory activities and weak to moderate acetylcholinestrease enzyme inhibition activity.
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Al-Taweel, A.M.; Perveen, S.; El-Shafae, A.M.; Fawzy, G.A.; Malik, A.; Afza, N.; Iqbal, L.; Latif, M. Bioactive Phenolic Amides from Celtis africana. Molecules 2012, 17, 2675-2682.
Al-Taweel AM, Perveen S, El-Shafae AM, Fawzy GA, Malik A, Afza N, Iqbal L, Latif M. Bioactive Phenolic Amides from Celtis africana. Molecules. 2012; 17(3):2675-2682.
Al-Taweel, Areej Mohammad; Perveen, Shagufta; El-Shafae, Azza Muhammed; Fawzy, Ghada Ahmed; Malik, Abdul; Afza, Nighat; Iqbal, Lubna; Latif, Mehreen. 2012. "Bioactive Phenolic Amides from Celtis africana." Molecules 17, no. 3: 2675-2682.