Next Article in Journal
Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.
Previous Article in Journal
Antioxidant Phenolic Compounds from Pu-erh Tea
Molecules 2012, 17(12), 14046-14057; doi:10.3390/molecules171214046
Article

4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis

1
,
1,†
,
1,* , 2
,
3
 and
3
Received: 24 September 2012 / Revised: 30 October 2012 / Accepted: 20 November 2012 / Published: 27 November 2012
(This article belongs to the Section Metabolites)
Download PDF [431 KB, uploaded 18 June 2014]

Abstract

Root extracts of Holostylis reniformis (Aristolochiaceae) yielded three new natural sesquiterpenes, a sesquiterpene with an unusual carbon skeleton, 4,5-seco-guaiane (7-epi-11-hydroxychabrolidione A, 1), a nine-membered lactone with new carbon skeleton (holostylactone, 2), and a new megastigmane [(6S,7E)-6,9-dihydroxy-10-(2'-hydroxy-ethoxy)-4,7-megastigmadien-3-one, 3], together with bulnesol and sitosterol-3-O-β-D-glucopyranoside. The structures of these compounds were determined by spectroscopic analyses and B3LYP/STO-3G** theoretical studies.
Keywords: Holostylis reniformis; Aristolochiaceae; sesquiterpene; 4,5-seco-guaiane; megastigmane Holostylis reniformis; Aristolochiaceae; sesquiterpene; 4,5-seco-guaiane; megastigmane
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplement

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Pereira, M.D.P.; da Silva, T.; Lopes, L.M.X.; Krettli, A.U.; Madureira, L.S.; Zukerman-Schpector, J. 4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis. Molecules 2012, 17, 14046-14057.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

Cited By

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert