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Molecules 2012, 17(12), 14058-14066; doi:10.3390/molecules171214058
Article

Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.

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6,*  and 1,2,3,7,*
Received: 22 October 2012 / Revised: 18 November 2012 / Accepted: 23 November 2012 / Published: 27 November 2012
(This article belongs to the Section Metabolites)
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Abstract

Two norcembranoidal diterpenes, 5-episinuleptolide acetate (1) and scabrolide D (2), were isolated from a Formosan octocoral identified as Sinularia sp. The structures of norcembranoids 1 and 2 were established by spectroscopic methods and by comparison of the spectral data with those of known analogues and 1 was proven to be a new natural product. Norcembranoid 1 was found to exhibit cytotoxicity toward a panel of tumor cells.
Keywords: Sinularia; norcembranoidal diterpene; cytotoxicity Sinularia; norcembranoidal diterpene; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Yen, W.-H.; Hu, L.-C.; Su, J.-H.; Lu, M.-C.; Twan, W.-H.; Yang, S.-Y.; Kuo, Y.-C.; Weng, C.-F.; Lee, C.-H.; Kuo, Y.-H.; Sung, P.-J. Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.. Molecules 2012, 17, 14058-14066.

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