Molecules 2012, 17(11), 13662-13672; doi:10.3390/molecules171113662
Article

Beckmann Rearrangement of Ketoximes Induced by Phenyl Dichlorophosphate at Ambient Temperature

Chun-Wei Kuo 1,2 , Min-Tsang Hsieh 3 , Shijay Gao 2 , Yi-Ming Shao 1 , Ching-Fa Yao 2  and Kak-Shan Shia 1,* email
1 Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County 35053, Taiwan 2 Department of Chemistry, National Taiwan Normal University, Taipei 116, Taiwan 3 Chinese Medicinal Research and Development Center, China Medical University Hospital, 2 Yude Road, Taichung 40447, Taiwan
* Author to whom correspondence should be addressed.
Received: 21 September 2012; in revised form: 12 November 2012 / Accepted: 14 November 2012 / Published: 20 November 2012
(This article belongs to the Section Organic Synthesis)
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Abstract: Upon treatment with phenyl dichlorophosphate (PhOP=OCl2) in acetonitrile at ambient temperature, a variety of ketoximes underwent a Beckmann rearrangement in an effective manner to afford the corresponding amides in moderate to high yields.
Keywords: Beckmann rearrangement; phenyl dichlorophosphate; ketoximes; ambient temperature

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MDPI and ACS Style

Kuo, C.-W.; Hsieh, M.-T.; Gao, S.; Shao, Y.-M.; Yao, C.-F.; Shia, K.-S. Beckmann Rearrangement of Ketoximes Induced by Phenyl Dichlorophosphate at Ambient Temperature. Molecules 2012, 17, 13662-13672.

AMA Style

Kuo C-W, Hsieh M-T, Gao S, Shao Y-M, Yao C-F, Shia K-S. Beckmann Rearrangement of Ketoximes Induced by Phenyl Dichlorophosphate at Ambient Temperature. Molecules. 2012; 17(11):13662-13672.

Chicago/Turabian Style

Kuo, Chun-Wei; Hsieh, Min-Tsang; Gao, Shijay; Shao, Yi-Ming; Yao, Ching-Fa; Shia, Kak-Shan. 2012. "Beckmann Rearrangement of Ketoximes Induced by Phenyl Dichlorophosphate at Ambient Temperature." Molecules 17, no. 11: 13662-13672.

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