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Molecules 2012, 17(10), 12357-12364; doi:10.3390/molecules171012357
Article

Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae

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Received: 13 August 2012 / Revised: 8 October 2012 / Accepted: 17 October 2012 / Published: 22 October 2012
(This article belongs to the Section Metabolites)
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Abstract

The investigation of secondary metabolites in liquid cultures of a recently discovered marine bacterium, Hasllibacter halocynthiae strain KME 002T, led to the isolation of two new cholic acid derivatives. The structures of these compounds were determined to be 3,3,12-trihydroxy-7-ketocholanic acid (1) and 3,3,12-trihydroxy-7-deoxycholanic acid (2) through HRFABMS and NMR data analyses.
Keywords: Hasllibacter halocynthiae; cholic acids; cholanic acid ketal; marine ascidian Hasllibacter halocynthiae; cholic acids; cholanic acid ketal; marine ascidian
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Kim, S.H.; Shin, Y.K.; Sohn, Y.C.; Kwon, H.C. Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae. Molecules 2012, 17, 12357-12364.

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