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Molecules 2012, 17(10), 12357-12364; doi:10.3390/molecules171012357

Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae

1
Natural Medicine Center, Korea Institute of Science and Technology (KIST), Gangneung 210-340, Korea
2
Division of Applied Marine Biotechnology and Engineering, Faculty of Marine Bioscience and Technology, Gangneung-Wonju National University, Gangneung 210-702, Korea
3
Aquaculture Management Division, National Fisheries Research and Development Institute, Busan 619-705, Korea
*
Author to whom correspondence should be addressed.
Received: 13 August 2012 / Revised: 8 October 2012 / Accepted: 17 October 2012 / Published: 22 October 2012
(This article belongs to the Section Natural Products)
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Abstract

The investigation of secondary metabolites in liquid cultures of a recently discovered marine bacterium, Hasllibacter halocynthiae strain KME 002T, led to the isolation of two new cholic acid derivatives. The structures of these compounds were determined to be 3,3,12-trihydroxy-7-ketocholanic acid (1) and 3,3,12-trihydroxy-7-deoxycholanic acid (2) through HRFABMS and NMR data analyses. View Full-Text
Keywords: Hasllibacter halocynthiae; cholic acids; cholanic acid ketal; marine ascidian Hasllibacter halocynthiae; cholic acids; cholanic acid ketal; marine ascidian
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Kim, S.H.; Shin, Y.K.; Sohn, Y.C.; Kwon, H.C. Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae. Molecules 2012, 17, 12357-12364.

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