Molecules 2012, 17(10), 12197-12205; doi:10.3390/molecules171012197
Communication

Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives

Maria de L. e Silva 1 email, Juceni P. David 1 email, Lidércia C. R. C. Silva 1 email, Rauldenis A. F. Santos 2 email, Jorge M. David 2,* email, Luciano S. Lima 3 email, Pedro S. Reis 4 email and Renato Fontana 5 email
1 Faculdade de Farmácia, Universidade Federal da Bahia, Rua Barão de Geremoabo, s/n, 41810-290, Salvador, BA, Brazil 2 Instituto de Quimica, Universidade Federal da Bahia, Rua Barão de Geremoabo, s/n, 41810-290, Salvador, BA, Brazil 3 Instituto Federal da Bahia, Campus Porto Seguro, Br 367, km 57.5 Fontana I - Porto Seguro, 45810-000, BA, Brazil 4 Núcleo de Pesquisa em Biodiversidade e Biotecnologia – Biotec, Universidade Federal do Piauí, Campus de Parnaíba. 64202-020, Parnaíba, PI, Brazil 5 Departamento de Ciências Biológicas, Universidade Estadual de Santa Cruz, Km 16 Rodovia Ilhéus-Itabuna 45662-000, Ilhéus, BA, Brazil
* Author to whom correspondence should be addressed.
Received: 14 September 2012; in revised form: 9 October 2012 / Accepted: 10 October 2012 / Published: 17 October 2012
(This article belongs to the Special Issue Triterpenes and Triterpenoids)
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Abstract: Betulinic, ursolic and oleanolic acids isolated from the aerial parts of Eriope blanchetii (Lamiaceae) were subjected to different esterification reactions, yielding 12 C-3 position ester derivatives. All compounds were identified using spectroscopic techniques, such as IR, 1H-NMR and MS. The derivatives were further investigated for their antioxidant level, Artemia salina lethality and antimicrobial activity.
Keywords: Eriope blanchetii; Lamiaceae; triterpene derivatives; Artemia salina lethality; antimicrobial activity

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Cite This Article

MDPI and ACS Style

Silva, M.L.; David, J.P.; Silva, L.C.R.C.; Santos, R.A.F.; David, J.M.; Lima, L.S.; Reis, P.S.; Fontana, R. Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives. Molecules 2012, 17, 12197-12205.

AMA Style

Silva ML, David JP, Silva LCRC, Santos RAF, David JM, Lima LS, Reis PS, Fontana R. Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives. Molecules. 2012; 17(10):12197-12205.

Chicago/Turabian Style

Silva, Maria L.; David, Juceni P.; Silva, Lidércia C. R. C.; Santos, Rauldenis A. F.; David, Jorge M.; Lima, Luciano S.; Reis, Pedro S.; Fontana, Renato. 2012. "Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives." Molecules 17, no. 10: 12197-12205.

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