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Molecules 2012, 17(10), 12197-12205; doi:10.3390/molecules171012197
Communication

Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives

1
, 1
, 1
, 2
, 2,* , 3
, 4
 and 5
1 Faculdade de Farmácia, Universidade Federal da Bahia, Rua Barão de Geremoabo, s/n, 41810-290, Salvador, BA, Brazil 2 Instituto de Quimica, Universidade Federal da Bahia, Rua Barão de Geremoabo, s/n, 41810-290, Salvador, BA, Brazil 3 Instituto Federal da Bahia, Campus Porto Seguro, Br 367, km 57.5 Fontana I - Porto Seguro, 45810-000, BA, Brazil 4 Núcleo de Pesquisa em Biodiversidade e Biotecnologia – Biotec, Universidade Federal do Piauí, Campus de Parnaíba. 64202-020, Parnaíba, PI, Brazil 5 Departamento de Ciências Biológicas, Universidade Estadual de Santa Cruz, Km 16 Rodovia Ilhéus-Itabuna 45662-000, Ilhéus, BA, Brazil
* Author to whom correspondence should be addressed.
Received: 14 September 2012 / Revised: 9 October 2012 / Accepted: 10 October 2012 / Published: 17 October 2012
(This article belongs to the Special Issue Triterpenes and Triterpenoids)
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Abstract

Betulinic, ursolic and oleanolic acids isolated from the aerial parts of Eriope blanchetii (Lamiaceae) were subjected to different esterification reactions, yielding 12 C-3 position ester derivatives. All compounds were identified using spectroscopic techniques, such as IR, 1H-NMR and MS. The derivatives were further investigated for their antioxidant level, Artemia salina lethality and antimicrobial activity.
Keywords: Eriope blanchetii; Lamiaceae; triterpene derivatives; Artemia salina lethality; antimicrobial activity Eriope blanchetii; Lamiaceae; triterpene derivatives; Artemia salina lethality; antimicrobial activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Silva, M.L.; David, J.P.; Silva, L.C.R.C.; Santos, R.A.F.; David, J.M.; Lima, L.S.; Reis, P.S.; Fontana, R. Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives. Molecules 2012, 17, 12197-12205.

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