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Molecules 2012, 17(10), 12197-12205; doi:10.3390/molecules171012197
Communication

Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives

1
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2,* , 3
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4
 and
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1 Faculdade de Farmácia, Universidade Federal da Bahia, Rua Barão de Geremoabo, s/n, 41810-290, Salvador, BA, Brazil 2 Instituto de Quimica, Universidade Federal da Bahia, Rua Barão de Geremoabo, s/n, 41810-290, Salvador, BA, Brazil 3 Instituto Federal da Bahia, Campus Porto Seguro, Br 367, km 57.5 Fontana I - Porto Seguro, 45810-000, BA, Brazil 4 Núcleo de Pesquisa em Biodiversidade e Biotecnologia – Biotec, Universidade Federal do Piauí, Campus de Parnaíba. 64202-020, Parnaíba, PI, Brazil 5 Departamento de Ciências Biológicas, Universidade Estadual de Santa Cruz, Km 16 Rodovia Ilhéus-Itabuna 45662-000, Ilhéus, BA, Brazil
* Author to whom correspondence should be addressed.
Received: 14 September 2012 / Revised: 9 October 2012 / Accepted: 10 October 2012 / Published: 17 October 2012
(This article belongs to the Special Issue Triterpenes and Triterpenoids)
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Abstract

Betulinic, ursolic and oleanolic acids isolated from the aerial parts of Eriope blanchetii (Lamiaceae) were subjected to different esterification reactions, yielding 12 C-3 position ester derivatives. All compounds were identified using spectroscopic techniques, such as IR, 1H-NMR and MS. The derivatives were further investigated for their antioxidant level, Artemia salina lethality and antimicrobial activity.
Keywords: Eriope blanchetii; Lamiaceae; triterpene derivatives; Artemia salina lethality; antimicrobial activity Eriope blanchetii; Lamiaceae; triterpene derivatives; Artemia salina lethality; antimicrobial activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Silva, M.L.; David, J.P.; Silva, L.C.R.C.; Santos, R.A.F.; David, J.M.; Lima, L.S.; Reis, P.S.; Fontana, R. Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives. Molecules 2012, 17, 12197-12205.

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