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Molecules 2012, 17(10), 11721-11728; doi:10.3390/molecules171011721

A New Saponin from Tea Seed Pomace (Camellia oleifera Abel) and Its Protective Effect on PC12 Cells

Key Laboratory of Tea Biochemistry & Biotechnology, Ministry of Education and Ministry of Agriculture, Anhui Agricultural University, Hefei 230036, China
College of Horticulture, Qingdao Agricultural University, Qingdao 266109, China
School of Life Science, Anhui Agricultural University, Hefei 230036, China
Authors to whom correspondence should be addressed.
Received: 31 August 2012 / Revised: 24 September 2012 / Accepted: 24 September 2012 / Published: 1 October 2012
(This article belongs to the Special Issue Triterpenes and Triterpenoids)
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A new triterpenoid saponin, oleiferasaponin A1, was isolated from tea seed pomace (Camellia oleifera Abel). The structure of oleiferasaponin A1 was elucidated on the basis of chemical and physicochemical evidence and was found to be 22-O-cis-2-hexenoyl-A1-barrigenol 3-O-[β-D-galactopyranosyl(1→2)] [β-D-glucopyranosyl(1→2)-α-L-arabinopyranosyl(1→3)]-β-D-glucopyranosiduronic acid. PC12 cells injured with H2O2 were used as the model to test the protective effects of oleiferasaponin A1. The results indicated that oleiferasaponin A1 can potentially prevent the H2O2-induced cell death of PC12 cells.
Keywords: Camellia oleifera; tea seed pomace; triterpenoid; saponin; PC12 cell Camellia oleifera; tea seed pomace; triterpenoid; saponin; PC12 cell

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Zhang, X.-F.; Han, Y.-Y.; Bao, G.-H.; Ling, T.-J.; Zhang, L.; Gao, L.-P.; Xia, T. A New Saponin from Tea Seed Pomace (Camellia oleifera Abel) and Its Protective Effect on PC12 Cells. Molecules 2012, 17, 11721-11728.

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