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Molecules 2011, 16(9), 7762-7772; doi:10.3390/molecules16097762

Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems

Department of Tea Science, Zhejiang University, Hangzhou 310058, China
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Received: 1 July 2011 / Revised: 28 August 2011 / Accepted: 8 September 2011 / Published: 9 September 2011
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Abstract

In the present study, polysaccharides named ALPS and ASPS were isolated from Ampelopsis grossedentata leaves and stems, respectively. Physicochemical properties, in vitro antioxidant activities and the inhibitory effects on α-glucosidase of ALPS and ASPS were investigated. It was found that both ALPS and ASPS were acid protein-bound heteropolysaccharides, although with considerably different chemical composition and molecular weight distribution. Meanwhile, in comparison with ALPS, ASPS exhibited stronger antioxidant activity and inhibitory potential against α-glucosidase according to the in vitro evaluation. Moreover, our results suggested that protein and uronic acid might, at least partly, contribute positively to the biological behavior of ALPS and ASPS.
Keywords: polysaccharides; Ampelopsis grossedentata; physicochemical properties; antioxidant activities; α-glucosidase inhibition polysaccharides; Ampelopsis grossedentata; physicochemical properties; antioxidant activities; α-glucosidase inhibition
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MDPI and ACS Style

Wang, Y.; Bian, X.; Park, J.; Ying, L.; Qian, L.; Xu, P. Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems. Molecules 2011, 16, 7762-7772.

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