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Molecules 2011, 16(7), 5989-5997; doi:10.3390/molecules16075989
Article

Three New Phytoecdysteroids Containing a Furan Ring from the Roots of Achyranthes bidentata Bl.

, , , ,  and *
Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine), Ministry of Education, No. 24 HePing Road, XiangFang District, Harbin 150040, China These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 10 May 2011 / Revised: 13 July 2011 / Accepted: 13 July 2011 / Published: 18 July 2011
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Abstract

Three new phytoecdysteroid compounds, named niuxixinsterone A (1), B (2) and C (3) with acetal functions in the side-chain were isolated from Achyranthes bidentata Bl. The structures were established as (20R,22R,24S)-20-O,22-O-(5′-hydroxymethyl)-furfurylidene-2β,3β,14α,25-tetrahydroxy-5β-ergost-7-en-6-one (1), (20R,22R)-20-O,22-O-(5′-hydroxymethyl)-furfurylidene-2β,3β,25-trihydroxy-14β-methyl-18-nor-5β-cholesta-7,12-dien-6-one (2) and (20R,22R,25R)-20-O,22-O-(5′-hydroxymethyl)-furfurylidene-2β, 3β,5β,14α,26-pentahydroxycholest-7-en-6-one (3) by means of spectroscopic evidence.
Keywords: Achyranthes bidentata Bl.; phytoecdysteroid; niuxixinsterone Achyranthes bidentata Bl.; phytoecdysteroid; niuxixinsterone
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Wang, Q.-H.; Yang, L.; Jiang, H.; Wang, Z.-B.; Yang, B.-Y.; Kuang, H.-X. Three New Phytoecdysteroids Containing a Furan Ring from the Roots of Achyranthes bidentata Bl.. Molecules 2011, 16, 5989-5997.

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