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Molecules 2011, 16(7), 5989-5997; doi:10.3390/molecules16075989
Article

Three New Phytoecdysteroids Containing a Furan Ring from the Roots of Achyranthes bidentata Bl.

, , , ,  and *
Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine), Ministry of Education, No. 24 HePing Road, XiangFang District, Harbin 150040, China These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 10 May 2011 / Revised: 13 July 2011 / Accepted: 13 July 2011 / Published: 18 July 2011
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Abstract

Three new phytoecdysteroid compounds, named niuxixinsterone A (1), B (2) and C (3) with acetal functions in the side-chain were isolated from Achyranthes bidentata Bl. The structures were established as (20R,22R,24S)-20-O,22-O-(5′-hydroxymethyl)-furfurylidene-2β,3β,14α,25-tetrahydroxy-5β-ergost-7-en-6-one (1), (20R,22R)-20-O,22-O-(5′-hydroxymethyl)-furfurylidene-2β,3β,25-trihydroxy-14β-methyl-18-nor-5β-cholesta-7,12-dien-6-one (2) and (20R,22R,25R)-20-O,22-O-(5′-hydroxymethyl)-furfurylidene-2β, 3β,5β,14α,26-pentahydroxycholest-7-en-6-one (3) by means of spectroscopic evidence.
Keywords: Achyranthes bidentata Bl.; phytoecdysteroid; niuxixinsterone Achyranthes bidentata Bl.; phytoecdysteroid; niuxixinsterone
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Wang, Q.-H.; Yang, L.; Jiang, H.; Wang, Z.-B.; Yang, B.-Y.; Kuang, H.-X. Three New Phytoecdysteroids Containing a Furan Ring from the Roots of Achyranthes bidentata Bl.. Molecules 2011, 16, 5989-5997.

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