Molecules 2011, 16(5), 3544-3551; doi:10.3390/molecules16053544
Article

Microwave-Assisted One-Step Synthesis of Fenamic Acid Hydrazides from the Corresponding Acids

Tarek Aboul-Fadl 1,* email, Hatem A. Abdel-Aziz 1 , Adnan Kadi 1 , Ahmed Bari 1 , Pervez Ahmad 1 , Tilal Al-Samani 1  and Seik Weng Ng 2
1 Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia 2 Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
* Author to whom correspondence should be addressed.
Received: 21 February 2011; in revised form: 30 March 2011 / Accepted: 2 April 2011 / Published: 28 April 2011
(This article belongs to the Section Organic Synthesis)
PDF Full-text Download PDF Full-Text [246 KB, uploaded 28 April 2011 10:40 CEST]
Abstract: A facile and efficient method for synthesis of fenamic acid hydrazides from their acids in one-step reaction under microwave irradiation and solvent-free conditions was developed. Compared with the two-step conventional heating method, the process was simple, the reaction time was very short and the yields were almost quantitative.
Keywords: fenamic acids; fenamic acid hydrazides; microwave irradiation; solvent-free reaction

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Aboul-Fadl, T.; Abdel-Aziz, H.A.; Kadi, A.; Bari, A.; Ahmad, P.; Al-Samani, T.; Ng, S.W. Microwave-Assisted One-Step Synthesis of Fenamic Acid Hydrazides from the Corresponding Acids. Molecules 2011, 16, 3544-3551.

AMA Style

Aboul-Fadl T, Abdel-Aziz HA, Kadi A, Bari A, Ahmad P, Al-Samani T, Ng SW. Microwave-Assisted One-Step Synthesis of Fenamic Acid Hydrazides from the Corresponding Acids. Molecules. 2011; 16(5):3544-3551.

Chicago/Turabian Style

Aboul-Fadl, Tarek; Abdel-Aziz, Hatem A.; Kadi, Adnan; Bari, Ahmed; Ahmad, Pervez; Al-Samani, Tilal; Ng, Seik Weng. 2011. "Microwave-Assisted One-Step Synthesis of Fenamic Acid Hydrazides from the Corresponding Acids." Molecules 16, no. 5: 3544-3551.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert