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Diterpene Glycosides from Stevia rebaudiana
The Coca-Cola Company, Organic Chemistry Department, Research and Technology, One Coca-Cola Plaza, Atlanta, GA 30313, USA
* Author to whom correspondence should be addressed.
Received: 24 March 2011; in revised form: 16 April 2011 / Accepted: 20 April 2011 / Published: 28 April 2011
Abstract: Three novel diterpene glycosides were isolated for the first time from the commercial extract of the leaves of Stevia rebaudiana, along with several known steviol glycosides, namely stevioside, rebaudiosides A-F, rubusoside and dulcoside A. The new compounds were identified as 13-[(2-O-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy] ent-kaur-15-en-19-oic acid (1), 13-[(2-O-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-16β-hydroxy-ent-kauran-19-oic acid (2) and 13-methyl-16-oxo-17-nor-ent-kauran-19-oic acid-β-D-glucopyranosyl ester (3) on the basis of extensive 2D NMR and MS spectroscopic data as well as chemical studies.
Keywords: Stevia rebaudiana; Compositae; Asteraceae; diterpenoid glycosides; spectral data; chemical studies
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MDPI and ACS Style
Prakash Chaturvedula, V.S.; Upreti, M.; Prakash, I. Diterpene Glycosides from Stevia rebaudiana. Molecules 2011, 16, 3552-3562.
Prakash Chaturvedula VS, Upreti M, Prakash I. Diterpene Glycosides from Stevia rebaudiana. Molecules. 2011; 16(5):3552-3562.
Prakash Chaturvedula, Venkata Sai; Upreti, Mani; Prakash, Indra. 2011. "Diterpene Glycosides from Stevia rebaudiana." Molecules 16, no. 5: 3552-3562.