Next Article in Journal
Microwave-Assisted Extraction of Phenolic Antioxidants from Potato Peels
Next Article in Special Issue
Wine and Grape Tannin Interactions with Salivary Proteins and Their Impact on Astringency: A Review of Current Research
Previous Article in Journal
Antiplasmodial Natural Products
Previous Article in Special Issue
The Ups and Downs of Tannins as Inhibitors of Poly(ADP-Ribose)glycohydrolase
Article Menu

Article Versions

Export Article

Open AccessReview
Molecules 2011, 16(3), 2191-2217; doi:10.3390/molecules16032191

Tannins of Constant Structure in Medicinal and Food Plants—Hydrolyzable Tannins and Polyphenols Related to Tannins

1
Emeritus Professor, Okayama University, Tsushima-naka, Okayama 700, Japan
2
Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Tsushima-naka, Okayama 700, Japan
*
Author to whom correspondence should be addressed.
Received: 19 January 2011 / Revised: 24 February 2011 / Accepted: 28 February 2011 / Published: 4 March 2011
(This article belongs to the Special Issue Tannins)
Download PDF [583 KB, 18 June 2014; original version 18 June 2014]

Abstract

In addition to the commonly used classification as hydrolyzable tannins and condensed tannins, tannins can also be categorized into two other types: polyphenols of constant chemical structure (Type A) and polyphenols of variable composition (Type B). Both types of tannins and related polyphenols account for a large part of plant polyphenols, but accurate structure-activity correlations on a molecular basis can be determined mainly for type A compounds, among which are hydrolysable tannins such as the ellagitannins and their oxidized congeners, some gallotannins, epigallocatechin gallate, caffetannins, etc. Among the activities determined on a molecular basis are the chemical, biological and pharmacological actions such as superoxide anion scavenging, apoptosis, antitumor, anti-EVB, anti-MRSA and anti-plasmin inhibitory activities, etc., in addition to their fundamental activities, i.e., binding to proteins, large molecular compounds and metallic ions, and antioxidant activities. Some structure-specific activities were found for the condensation of dehydroellagitannins with co-existing compounds under mild conditions, and the host-mediated antitumor actions of ellagitannin oligomers. Structures and activities of metabolites of geraniin, a dehydroellagitannin, were revealed. Some stilbenoids and phlorotannins of firm structures have been known to have many activities similar to those of the type A tannins.
Keywords: tannin and polyphenol; type A tannin; type B tannin; classification; biological and pharmacological properties tannin and polyphenol; type A tannin; type B tannin; classification; biological and pharmacological properties
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Okuda, T.; Ito, H. Tannins of Constant Structure in Medicinal and Food Plants—Hydrolyzable Tannins and Polyphenols Related to Tannins. Molecules 2011, 16, 2191-2217.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top