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Molecules 2011, 16(10), 8646-8653; doi:10.3390/molecules16108646
Article

Two New Epoxysteroids from Helianthus tuberosus

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Received: 5 September 2011; in revised form: 10 October 2011 / Accepted: 11 October 2011 / Published: 13 October 2011
(This article belongs to the Special Issue Steroids)
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Abstract: Two new epoxy steroids, 5α,8α-epidioxy-22β,23β-epoxyergosta-6-en-3β-ol (1) and 5α,8α-epidioxy-22α,23α-epoxyergosta-6-en-3β-ol (2), and ten known steroids including (24R)-5α,8α-epidioxyergosta-6-en-3β-ol (3), (22E,24R)-5α,8α-epidioxyergosta-6,22-dien-3β-ol (4), (22E,24R)-5α,8α-epidioxyergosta-6,9(11),22-trien-3β-ol (5), β-sitosterol (6), sitost-5-en-3β-ol acetate (7), 7α-hydroxysitosterol (8), schleicheol 2 (9), (24R)-24-ethyl-5α-cholestane-3β,5α,6β-triol (10), 7α-hydroxystigmasterol (11), and stigmasterol (12) were isolated from Helianthus tuberosus grown in Laizhou salinized land of coastal zone of Bohai Sea, China. The structures of these compounds were unambiguously established by 1D, 2D NMR and mass spectroscopic techniques. The new compounds 1 and 2 exhibited weak antibacterial activity and no antifungal activity.
Keywords: Helianthus tuberosus; steroid; 5α,8α-epidioxy-22β,23β-epoxyergosta-6-en-3β-ol; 5α,8α-epidioxy-22α,23α-epoxyergosta-6-en-3β-ol Helianthus tuberosus; steroid; 5α,8α-epidioxy-22β,23β-epoxyergosta-6-en-3β-ol; 5α,8α-epidioxy-22α,23α-epoxyergosta-6-en-3β-ol
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Li, X.-D.; Miao, F.-P.; Ji, N.-Y. Two New Epoxysteroids from Helianthus tuberosus. Molecules 2011, 16, 8646-8653.

AMA Style

Li X-D, Miao F-P, Ji N-Y. Two New Epoxysteroids from Helianthus tuberosus. Molecules. 2011; 16(10):8646-8653.

Chicago/Turabian Style

Li, Xiao-Dong; Miao, Feng-Ping; Ji, Nai-Yun. 2011. "Two New Epoxysteroids from Helianthus tuberosus." Molecules 16, no. 10: 8646-8653.



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