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Molecules 2010, 15(9), 6638-6677; doi:10.3390/molecules15096638
Review

Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides

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Received: 2 June 2010 / Revised: 13 September 2010 / Accepted: 15 September 2010 / Published: 21 September 2010
(This article belongs to the Special Issue Ring-Closing Metathesis)
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Abstract

Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM.
Keywords: ring-closing metathesis; peptides; structure; pharmacological properties ring-closing metathesis; peptides; structure; pharmacological properties
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Jacobsen, Ø.; Klaveness, J.; Rongved, P. Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides. Molecules 2010, 15, 6638-6677.

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