Molecules 2010, 15(6), 4094-4101; doi:10.3390/molecules15064094
Article

An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives

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Received: 26 April 2010; in revised form: 14 May 2010 / Accepted: 24 May 2010 / Published: 7 June 2010
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Reaction of allyl bromide (Z)-1 and (Z)-2 with N-substituted hydroxylamine hydrochlorides in presence of tert-butoxide in tert-butanol at reflux provides a short and effective route to [1,2]isoxazolidin-5-ones 3 and [1,2]oxazin-6-ones 4.
Keywords: functional allyl bromides; conjugate addition; N-substituted hydroxylamines; isoxazolidin-5-ones; oxazin-6-ones
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MDPI and ACS Style

Beltaïef, I.; Arfaoui, A.; Amri, H. An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives. Molecules 2010, 15, 4094-4101.

AMA Style

Beltaïef I, Arfaoui A, Amri H. An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives. Molecules. 2010; 15(6):4094-4101.

Chicago/Turabian Style

Beltaïef, Imen; Arfaoui, Aïcha; Amri, Hassen. 2010. "An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives." Molecules 15, no. 6: 4094-4101.

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