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This paper was retracted on 17 October 2014, see Molecules 2014, 19(10), 16810.

Molecules 2010, 15(6), 4094-4101; doi:10.3390/molecules15064094
Article

An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives

,  and *
Laboratoire de Chimie Organique et Organométallique, Université de Tunis El Manar, Faculté des Sciences, Campus Universitaire 2092-Tunis, Tunisia
* Author to whom correspondence should be addressed.
Received: 26 April 2010 / Revised: 14 May 2010 / Accepted: 24 May 2010 / Published: 7 June 2010
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Abstract

Reaction of allyl bromide (Z)-1 and (Z)-2 with N-substituted hydroxylamine hydrochlorides in presence of tert-butoxide in tert-butanol at reflux provides a short and effective route to [1,2]isoxazolidin-5-ones 3 and [1,2]oxazin-6-ones 4.
Keywords: functional allyl bromides; conjugate addition; N-substituted hydroxylamines; isoxazolidin-5-ones; oxazin-6-ones functional allyl bromides; conjugate addition; N-substituted hydroxylamines; isoxazolidin-5-ones; oxazin-6-ones
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Beltaïef, I.; Arfaoui, A.; Amri, H. An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives. Molecules 2010, 15, 4094-4101.

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