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Molecules 2010, 15(3), 1882-1890; doi:10.3390/molecules15031882
Article

Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents

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Received: 11 January 2010 / Revised: 11 March 2010 / Accepted: 12 March 2010 / Published: 15 March 2010
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Abstract

A variety of novel bicyclic and tricyclic pyrimidine derivatives was obtained via reaction of 6-amino-2-thioxo-1H-pyrimidine-4-one (1) with a different reagents. The antimicrobial and anti-inflammatory activities of some of the synthesized compounds were tested.
Keywords: pyrimidine; 6-amino-2-thioxo-1H-pyrimidine-4-one; antimicrobial; anti-inflammatory pyrimidine; 6-amino-2-thioxo-1H-pyrimidine-4-one; antimicrobial; anti-inflammatory
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Mohamed, M.S.; Awad, S.M.; Sayed, A.I. Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents. Molecules 2010, 15, 1882-1890.

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