Molecules 2010, 15(3), 1882-1890; doi:10.3390/molecules15031882
Article

Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents

Mosaad S. Mohamed, Samir M. Awad and Amira Ibrahim Sayed* email
Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Helwan, Egypt
* Author to whom correspondence should be addressed.
Received: 11 January 2010; in revised form: 11 March 2010 / Accepted: 12 March 2010 / Published: 15 March 2010
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Abstract: A variety of novel bicyclic and tricyclic pyrimidine derivatives was obtained via reaction of 6-amino-2-thioxo-1H-pyrimidine-4-one (1) with a different reagents. The antimicrobial and anti-inflammatory activities of some of the synthesized compounds were tested.
Keywords: pyrimidine; 6-amino-2-thioxo-1H-pyrimidine-4-one; antimicrobial; anti-inflammatory

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Cite This Article

MDPI and ACS Style

Mohamed, M.S.; Awad, S.M.; Sayed, A.I. Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents. Molecules 2010, 15, 1882-1890.

AMA Style

Mohamed MS, Awad SM, Sayed AI. Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents. Molecules. 2010; 15(3):1882-1890.

Chicago/Turabian Style

Mohamed, Mosaad S.; Awad, Samir M.; Sayed, Amira Ibrahim. 2010. "Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents." Molecules 15, no. 3: 1882-1890.

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