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Molecules 2010, 15(3), 1882-1890; doi:10.3390/molecules15031882
Article

Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents

,  and *
Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Helwan, Egypt
* Author to whom correspondence should be addressed.
Received: 11 January 2010 / Revised: 11 March 2010 / Accepted: 12 March 2010 / Published: 15 March 2010
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Abstract

A variety of novel bicyclic and tricyclic pyrimidine derivatives was obtained via reaction of 6-amino-2-thioxo-1H-pyrimidine-4-one (1) with a different reagents. The antimicrobial and anti-inflammatory activities of some of the synthesized compounds were tested.
Keywords: pyrimidine; 6-amino-2-thioxo-1H-pyrimidine-4-one; antimicrobial; anti-inflammatory pyrimidine; 6-amino-2-thioxo-1H-pyrimidine-4-one; antimicrobial; anti-inflammatory
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Mohamed, M.S.; Awad, S.M.; Sayed, A.I. Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents. Molecules 2010, 15, 1882-1890.

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