Secondary Metabolites from Inula britannica L. and Their Biological Activities

doi:10.3390/molecules15031562

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Molecules 2010, 15(3), 1562-1577; doi:10.3390/molecules15031562

Review

Secondary Metabolites from Inula britannica L. and Their Biological Activities

Abdul Latif Khan^1,2, Javid Hussain², Muhammad Hamayun¹, Syed Abdullah Gilani⁴, Shabir Ahmad², Gauhar Rehman³, Yoon-Ha Kim¹, Sang-Mo Kang¹ and In-Jung Lee^1,*

¹ School of Applied Biosciences, Kyungpook National University, Korea ² Department of Chemistry, Kohat University of Science & Technology, Kohat, Pakistan ³ Department of Genetic Engineering, School of Life Sciences & Biotechnology, Kyungpook National University, Korea ⁴ Department of Biotechnology, Kohat University of Science & Technology, Kohat, Pakistan

* Author to whom correspondence should be addressed.

Received: 4 January 2010; in revised form: 25 January 2010 / Accepted: 28 January 2010 / Published: 10 March 2010

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Abstract: Inula britannica L., family Asteraceae, is used in traditional Chinese and Kampo Medicines for various diseases. Flowers or the aerial parts are a rich source of secondary metabolites. These consist mainly of terpenoids (sesquiterpene lactones and dimmers, diterpenes and triterpenoids) and flavonoids. The isolated compounds have shown diverse biological activities: anticancer, antioxidant, anti-inflammatory, neuroprotective and hepatoprotective activities. This review provides information on isolated bioactive phytochemicals and pharmacological potentials of I. britannica.

Keywords: I. britannica; sesquiterpenoids; flavonoids; triterpenoids; anticancer; antioxidant; anti-inflammatory; hepatoprotective; neuroprotective

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MDPI and ACS Style

Khan, A.L.; Hussain, J.; Hamayun, M.; Gilani, S.A.; Ahmad, S.; Rehman, G.; Kim, Y.-H.; Kang, S.-M.; Lee, I.-J. Secondary Metabolites from Inula britannica L. and Their Biological Activities. Molecules 2010, 15, 1562-1577.

AMA Style

Khan AL, Hussain J, Hamayun M, Gilani SA, Ahmad S, Rehman G, Kim Y-H, Kang S-M, Lee I-J. Secondary Metabolites from Inula britannica L. and Their Biological Activities. Molecules. 2010; 15(3):1562-1577.

Chicago/Turabian Style

Khan, Abdul Latif; Hussain, Javid; Hamayun, Muhammad; Gilani, Syed Abdullah; Ahmad, Shabir; Rehman, Gauhar; Kim, Yoon-Ha; Kang, Sang-Mo; Lee, In-Jung. 2010. "Secondary Metabolites from Inula britannica L. and Their Biological Activities." Molecules 15, no. 3: 1562-1577.

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