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Molecules 2010, 15(3), 1562-1577; doi:10.3390/molecules15031562
Review

Secondary Metabolites from Inula britannica L. and Their Biological Activities

1,2, 2, 1, 4, 2, 3, 1, 1 and 1,*
1 School of Applied Biosciences, Kyungpook National University, Korea 2 Department of Chemistry, Kohat University of Science & Technology, Kohat, Pakistan 3 Department of Genetic Engineering, School of Life Sciences & Biotechnology, Kyungpook National University, Korea 4 Department of Biotechnology, Kohat University of Science & Technology, Kohat, Pakistan
* Author to whom correspondence should be addressed.
Received: 4 January 2010 / Revised: 25 January 2010 / Accepted: 28 January 2010 / Published: 10 March 2010
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Abstract

Inula britannica L., family Asteraceae, is used in traditional Chinese and Kampo Medicines for various diseases. Flowers or the aerial parts are a rich source of secondary metabolites. These consist mainly of terpenoids (sesquiterpene lactones and dimmers, diterpenes and triterpenoids) and flavonoids. The isolated compounds have shown diverse biological activities: anticancer, antioxidant, anti-inflammatory, neuroprotective and hepatoprotective activities. This review provides information on isolated bioactive phytochemicals and pharmacological potentials of I. britannica.
Keywords: I. britannica; sesquiterpenoids; flavonoids; triterpenoids; anticancer; antioxidant; anti-inflammatory; hepatoprotective; neuroprotective I. britannica; sesquiterpenoids; flavonoids; triterpenoids; anticancer; antioxidant; anti-inflammatory; hepatoprotective; neuroprotective
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Khan, A.L.; Hussain, J.; Hamayun, M.; Gilani, S.A.; Ahmad, S.; Rehman, G.; Kim, Y.-H.; Kang, S.-M.; Lee, I.-J. Secondary Metabolites from Inula britannica L. and Their Biological Activities. Molecules 2010, 15, 1562-1577.

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