Molecules 2010, 15(3), 1562-1577; doi:10.3390/molecules15031562
Secondary Metabolites from Inula britannica L. and Their Biological Activities
1
School of Applied Biosciences, Kyungpook National University, Korea
2
Department of Chemistry, Kohat University of Science & Technology, Kohat, Pakistan
3
Department of Genetic Engineering, School of Life Sciences & Biotechnology, Kyungpook National University, Korea
4
Department of Biotechnology, Kohat University of Science & Technology, Kohat, Pakistan
*
Author to whom correspondence should be addressed.
Received: 4 January 2010 / Revised: 25 January 2010 / Accepted: 28 January 2010 / Published: 10 March 2010
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Abstract
Inula britannica L., family Asteraceae, is used in traditional Chinese and Kampo Medicines for various diseases. Flowers or the aerial parts are a rich source of secondary metabolites. These consist mainly of terpenoids (sesquiterpene lactones and dimmers, diterpenes and triterpenoids) and flavonoids. The isolated compounds have shown diverse biological activities: anticancer, antioxidant, anti-inflammatory, neuroprotective and hepatoprotective activities. This review provides information on isolated bioactive phytochemicals and pharmacological potentials of I. britannica.Keywords:
I. britannica; sesquiterpenoids; flavonoids; triterpenoids; anticancer; antioxidant; anti-inflammatory; hepatoprotective; neuroprotective
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Khan, A.L.; Hussain, J.; Hamayun, M.; Gilani, S.A.; Ahmad, S.; Rehman, G.; Kim, Y.-H.; Kang, S.-M.; Lee, I.-J. Secondary Metabolites from Inula britannica L. and Their Biological Activities. Molecules 2010, 15, 1562-1577.
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