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Molecules 2010, 15(2), 672-679; doi:10.3390/molecules15020672
Communication

A New Flavone C-Glycoside from Clematis rehderiana

1
,
2
,
1, 1 and 1,*
1 State Key Laboratory of Phytochemistry and Plant Resources of West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China 2 Key Laboratory of Marine Bioresources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
* Author to whom correspondence should be addressed.
Received: 24 December 2009 / Revised: 28 January 2010 / Accepted: 29 January 2010 / Published: 29 January 2010
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Abstract

A new flavone C-glycoside, isovitexin 6″-O-E-p-coumarate (1) and two known flavonoid glycosides—quercetin 3-O-β-D-glucuronopyranoside (2) and isoorientin (3)—were isolated from an ethanol extract of aerial parts of Clematis rehderiana. Their structures were determined by spectroscopic methods. The antioxidant effects of the two flavone C-glycosides were evaluated by both the MTT and DPPH assays. Compound 1 showed potent activities against H2O2-induced impairment in PC12 cells within the concentration range tested, whereas compound 3 scavenged DPPH radical strongly, with an IC50 value of 13.5 μM.
Keywords: Clematis rehderiana; flavonoide glycosides; antioxidant Clematis rehderiana; flavonoide glycosides; antioxidant
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Du, Z.-Z.; Yang, X.-W.; Han, H.; Cai, X.-H.; Luo, X.-D. A New Flavone C-Glycoside from Clematis rehderiana. Molecules 2010, 15, 672-679.

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