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Molecules 2010, 15(12), 9197-9204; doi:10.3390/molecules15129197

An Efficient Synthesis of 1-Aryl-3-(indole-3-yl)-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-one Catalyzed by a Brønsted Acid Ionic Liquid

1
Physics and Chemistry Detecting Center, Xinjiang University, 830046 Urumqi, China
2
Key Laboratory of Oil and Gas Fine Chemicals Ministry of Education, School of Chemistry and Chemical Engineering, Xinjiang University, 830046 Urumqi, China
*
Author to whom correspondence should be addressed.
Received: 11 October 2010 / Revised: 3 December 2010 / Accepted: 7 December 2010 / Published: 10 December 2010
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Abstract

An efficient synthesis of novel 1-aryl-3-(indole-3-yl)-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-ones from indoles and 1-aryl-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-one using a Brønsted acid ionic liquid [Sbmim][HSO4] as catalyst is described. Satisfactory results with excellent yields and short reaction time were obtained in the experiments. The catalyst could be recovered conveniently and reused efficiently.
Keywords: Brønsted acidic ionic liquid; Michael reaction; indoles; 1,2,3-triazole Brønsted acidic ionic liquid; Michael reaction; indoles; 1,2,3-triazole
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Liu, C.-J.; Yu, C.-J. An Efficient Synthesis of 1-Aryl-3-(indole-3-yl)-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-one Catalyzed by a Brønsted Acid Ionic Liquid. Molecules 2010, 15, 9197-9204.

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