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Antiseptic Activity and Phenolic Constituents of the Aerial Parts of Vitex negundo var. cannabifolia
Key Laboratory of Tea Biochemistry and Biotechnology of Ministry of Education and Ministry of Agriculture, Anhui Agricultural University, 130 West Changjiang Road, Hefei 230036, China
These authors contributed equally to the paper.
* Author to whom correspondence should be addressed.
Received: 15 October 2010; in revised form: 11 November 2010 / Accepted: 15 November 2010 / Published: 18 November 2010
Abstract: Four phenolics, salviaplebeiaside (1), γ-tocopherol (2), chrysosplenol-D (4), and isovitexin (5), along with α-tocoquinone (3) and β-sitosterol (6) were isolated from the aerial parts of Vitex negundo var. cannabifolia. The isolation was performed using bio-assay tracking experiments. The structures of compounds 1-5 were established by spectroscopic means. The antibacterial activities of the compounds were assessed against Escherichia coli, Bacillus subtilis, Micrococcus tetragenus and Pseudomonas fluorescens. Chrysosplenol-D (4) exhibited activities against all the four spoilage microorganisms.
Keywords: Vitex negundo var. cannabifolia; Verbenaceae; phenolics; antibacterial activities; spoilage microorganisms
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Ling, T.-J.; Ling, W.-W.; Chen, Y.-J.; Wan, X.-C.; Xia, T.; Du, X.-F.; Zhang, Z.-Z. Antiseptic Activity and Phenolic Constituents of the Aerial Parts of Vitex negundo var. cannabifolia. Molecules 2010, 15, 8469-8477.
Ling T-J, Ling W-W, Chen Y-J, Wan X-C, Xia T, Du X-F, Zhang Z-Z. Antiseptic Activity and Phenolic Constituents of the Aerial Parts of Vitex negundo var. cannabifolia. Molecules. 2010; 15(11):8469-8477.
Ling, Tie-Jun; Ling, Wei-Wei; Chen, Yuan-Jun; Wan, Xiao-Chun; Xia, Tao; Du, Xian-Feng; Zhang, Zheng-Zhu. 2010. "Antiseptic Activity and Phenolic Constituents of the Aerial Parts of Vitex negundo var. cannabifolia." Molecules 15, no. 11: 8469-8477.