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Molecules 2010, 15(1), 12-26; doi:10.3390/molecules15010012
Article

Synthesis and in Vitro Cytotoxic Activity of Compounds with Pro-Apoptotic Potential

1, 1,2, 2, 2, 1 and 1,3,*
Received: 24 November 2009; in revised form: 12 December 2009 / Accepted: 18 December 2009 / Published: 24 December 2009
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Abstract: In our search for new anticancer therapies, some compounds synthesized in our lab were selected and their potential cytotoxic activity was evaluated in vitro against two cancer cells lines including a solid tumor (UACC-62, melanoma) and a human lymphoma (JURKAT). Compounds showing cytotoxic activity were subjected to an apoptosis assay. Two compounds showed promising results.
Keywords: carbohydrates; furan derivatives; cytotoxic activity; anti-tumor; apoptosis carbohydrates; furan derivatives; cytotoxic activity; anti-tumor; apoptosis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Apicela Soares, G.; Barbosa de Oliveira, R.; Fernandes de Andrade, S.; Alves, R.J.; Leomar Zani, C.; De Souza-Fagundes, E.M. Synthesis and in Vitro Cytotoxic Activity of Compounds with Pro-Apoptotic Potential. Molecules 2010, 15, 12-26.

AMA Style

Apicela Soares G, Barbosa de Oliveira R, Fernandes de Andrade S, Alves RJ, Leomar Zani C, De Souza-Fagundes EM. Synthesis and in Vitro Cytotoxic Activity of Compounds with Pro-Apoptotic Potential. Molecules. 2010; 15(1):12-26.

Chicago/Turabian Style

Apicela Soares, Gisell; Barbosa de Oliveira, Renata; Fernandes de Andrade, Saulo; Alves, Ricardo José; Leomar Zani, Carlos; De Souza-Fagundes, Elaine Maria. 2010. "Synthesis and in Vitro Cytotoxic Activity of Compounds with Pro-Apoptotic Potential." Molecules 15, no. 1: 12-26.


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