Molecules 2009, 14(8), 2918-2926; doi:10.3390/molecules14082918
Article

Cross-Cyclotrimerization with Two Nitriles as a Synthetic Pathway to Unsymmetrically 3,3’-Disubstituted bis(Tetrahydroisoquinolines)

1 and 1,2,* email
Received: 10 July 2009; in revised form: 31 July 2009 / Accepted: 3 August 2009 / Published: 10 August 2009
(This article belongs to the Special Issue Microwave Assisted Synthesis)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Microwave assisted CpCo(CO)2 catalyzed cross-cyclotrimerizations of 1,7,9,15-hexadecatetrayne with two different nitriles to give unsymmetrically substituted bis(tetrahydroisoquinolines) was studied. The reaction proceeded with a range of alkyl and aryl nitriles with reasonable isolated yields.
Keywords: cyclotrimerization; cobalt; microwave heating; pyridines
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MDPI and ACS Style

Kadlčíková, A.; Kotora, M. Cross-Cyclotrimerization with Two Nitriles as a Synthetic Pathway to Unsymmetrically 3,3’-Disubstituted bis(Tetrahydroisoquinolines). Molecules 2009, 14, 2918-2926.

AMA Style

Kadlčíková A, Kotora M. Cross-Cyclotrimerization with Two Nitriles as a Synthetic Pathway to Unsymmetrically 3,3’-Disubstituted bis(Tetrahydroisoquinolines). Molecules. 2009; 14(8):2918-2926.

Chicago/Turabian Style

Kadlčíková, Aneta; Kotora, Martin. 2009. "Cross-Cyclotrimerization with Two Nitriles as a Synthetic Pathway to Unsymmetrically 3,3’-Disubstituted bis(Tetrahydroisoquinolines)." Molecules 14, no. 8: 2918-2926.


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