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Coumarins from Angelica Lucida L. - Antibacterial Activities
Department of Pharmacognosy with Medicinal Plant Laboratory, Skubiszewski Medicinal University of Lublin, 1 Chodzki str., 20-093, Poland
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev str., bl.9, 1113 Sofia, Bulgaria
Division of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, University of Athens, Athens 15771, Greece
* Author to whom correspondence should be addressed.
Received: 1 July 2009; in revised form: 20 July 2009 / Accepted: 20 July 2009 / Published: 27 July 2009
Abstract: The first phytochemical investigation of the fruits of Angelica lucida has led to the isolation and characterization of five known coumarins (imperatorin, isoimperatorin, heraclenol, oxypeucedanin hydrate and heraclenin). All isolated compounds were identified by means of spectral and literature data. The extracts and the isolated constituents from A. lucida have been also evaluated for their antimicrobial activity against six Gram positive and negative bacteria, two oral pathogens and three human pathogenic fungi, exhibiting an interesting antimicrobial profile.
Keywords: Angelica lucida; apiaceae; coumarins; antibacterial activity
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Widelski, J.; Popova, M.; Graikou, K.; Glowniak, K.; Chinou, I. Coumarins from Angelica Lucida L. - Antibacterial Activities. Molecules 2009, 14, 2729-2734.
Widelski J, Popova M, Graikou K, Glowniak K, Chinou I. Coumarins from Angelica Lucida L. - Antibacterial Activities. Molecules. 2009; 14(8):2729-2734.
Widelski, Jaroslaw; Popova, Milena; Graikou, Konstantia; Glowniak, Kazimierz; Chinou, Ioanna. 2009. "Coumarins from Angelica Lucida L. - Antibacterial Activities." Molecules 14, no. 8: 2729-2734.