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Molecules 2009, 14(4), 1627-1638; doi:10.3390/molecules14041627
Article

Protective Effects of Celery Juice in Treatments with Doxorubicin

1, 2,* , 3, 4 and 5
1 Institute for Child and Youth Health Care of Vojvodina, Department of Hematology/Oncology, Novi Sad, Republic of Serbia 2 Department of Chemistry, Faculty of Science, University of Novi Sad, 21000 Novi Sad, Republic of Serbia 3 Medical Faculty and Department of Pharmacology and Toxicology, University of Novi Sad, Republic of Serbia 4 Institute of Pharmacology, Faculty of Medicine, University of Pristina (Kosovska Mitrovica), Republic of Serbia 5 Department of Surgery, Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Republic of Serbia
* Author to whom correspondence should be addressed.
Received: 3 March 2009 / Revised: 14 April 2009 / Accepted: 23 April 2009 / Published: 24 April 2009
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Abstract

The aim of this work was to investigate possible protective effect of celery juice in doxorubicin treatment. The following biochemical parameters were determined: content of reduced glutathione, activities of catalase, xanthine oxidase, glutathione peroxidase, peroxidase, and lipid peroxidation intensity in liver homogenate and blood hemolysate. We examined influence of diluted pure celery leaves and roots juices and their combinations with doxorubicine on analyzed biochemical parameters. Celery roots and leaves juices influenced the examined biochemical parameters and showed protective effects when applied with doxorubicine.
Keywords: Celery juice; Doxorubicin; Reduced glutathione; Lipid peroxidation; Catalase Celery juice; Doxorubicin; Reduced glutathione; Lipid peroxidation; Catalase
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Kolarovic, J.; Popovic, M.; Mikov, M.; Mitic, R.; Gvozdenovic, L. Protective Effects of Celery Juice in Treatments with Doxorubicin. Molecules 2009, 14, 1627-1638.

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