Molecules 2008, 13(4), 1011-1024; doi:10.3390/molecules13041011
Article

Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles

Received: 8 April 2008; in revised form: 22 April 2008 / Accepted: 22 April 2008 / Published: 29 April 2008
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Several 1,3-diaryl-5-(cyano-, aminocarbonyl- and ethoxycarbonyl-)-2-pyrazoline, pyrrolo[3,4-c]pyrazole-4,6-dione and 1,3,4,5-tetraaryl-2-pyrazoline derivativeswere prepared by the reaction of nitrilimine with different dipolarophilic reagents. The newcompounds were characterized using IR, 1H-NMR, 13C-NMR and mass spectra. Biologicalscreening of some compounds is reported.
Keywords: Pyrazoline; pyrrolo[3; 4-c]pyrazole-4; 6-dione; nitrilimine; dipolarophile; biological activity
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MDPI and ACS Style

Abunada, N.M.; Hassaneen, H.M.; Kandile, N.G.; Miqdad, O.A. Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles. Molecules 2008, 13, 1011-1024.

AMA Style

Abunada NM, Hassaneen HM, Kandile NG, Miqdad OA. Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles. Molecules. 2008; 13(4):1011-1024.

Chicago/Turabian Style

Abunada, Nada M.; Hassaneen, Hamdi M.; Kandile, Nadia G.; Miqdad, Omar A. 2008. "Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles." Molecules 13, no. 4: 1011-1024.

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