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Progress in the Studies on Rutaecarpine
College of Pharmacy, Yeungnam University, Gyeongsan 712-749 Korea
* Author to whom correspondence should be addressed.
Received: 1 January 2008; in revised form: 1 February 2008 / Accepted: 2 February 2008 / Published: 6 February 2008
(This article belongs to the Special Issue Alkaloids
Abstract: Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodiarutaecarpa and related herbs, which has shown a variety of intriguing biological propertiessuch as anti-thrombotic, anticancer, anti-inflammatory and analgesic, anti-obesity andthermoregulatory, vasorelaxing activity, as well as effects on the cardiovascular andendocrine systems. Recent progress in the studies on the isolation, synthesis, structureactivityrelationship studies, biological activities and metabolism of rutaecarpine arereviewed.
Keywords: Alkaloid; Rutaceae; rutaecarpine.
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Lee, S.H.; Son, J.-K.; Jeong, B.S.; Jeong, T.-C.; Chang, H.W.; Lee, E.-S.; Jahng, Y. Progress in the Studies on Rutaecarpine. Molecules 2008, 13, 272-300.
Lee SH, Son J-K, Jeong BS, Jeong T-C, Chang HW, Lee E-S, Jahng Y. Progress in the Studies on Rutaecarpine. Molecules. 2008; 13(2):272-300.
Lee, Seung H.; Son, Jong-Keun; Jeong, Byeong S.; Jeong, Tae-Cheon; Chang, Hyeon W.; Lee, Eung-Seok; Jahng, Yurngdong. 2008. "Progress in the Studies on Rutaecarpine." Molecules 13, no. 2: 272-300.