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Correction published on 15 January 2009, see Molecules 2009, 14(1), 412-413.

Open AccessArticle
Molecules 2008, 13(12), 3033-3039; doi:10.3390/molecules13123033

A New Cytotoxic Pregnanone from Calotropis gigantea

Institute of Crops Genetic Resources, Chinese Academy of Tropical Agricultural Sciences, Danzhou, 571737, P. R. China
Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, P. R. China
Authors to whom correspondence should be addressed.
Received: 25 September 2008 / Revised: 26 November 2008 / Accepted: 3 December 2008 / Published: 4 December 2008
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A new pregnanone, named calotropone (1), was isolated from the EtOH extract of the roots of Calotropis gigantea L. together with a known cardiac glycoside. The structures were elucidated by a study of their physical and spectral data. Compounds 1 and 2 displayed inhibitory effects towards chronic myelogenous leukemia K562 and human gastric cancer SGC-7901 cell lines. View Full-Text
Keywords: Calotropis gigantea L.; Calotropone; Cytotoxicity Calotropis gigantea L.; Calotropone; Cytotoxicity

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Wang, Z.-N.; Wang, M.-Y.; Mei, W.-L.; Han, Z.; Dai, H.-F. A New Cytotoxic Pregnanone from Calotropis gigantea. Molecules 2008, 13, 3033-3039.

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