Molecules 2007, 12(4), 782-796; doi:10.3390/12040782
Article

Complexes of 3dn Metal Ions with Thiosemicarbazones: Synthesis and Antimicrobial Activity

1,* email, 2email, 3email and 4email
Received: 27 February 2007; in revised form: 5 April 2007 / Accepted: 12 April 2007 / Published: 17 April 2007
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The chelating behavior of the thiosemicarbazone derivatives of 2-hydroxy-8-R-tricyclo[7.3.1.0.2,7]tridecane-13-one (where R = H, CH3, C6H5) towards Co(II), Ni(II) and Cu(II) has been investigated by elemental analysis, molar conductivity measurements, UV-VIS, IR, ESR spectroscopy and thermal studies. It was deduced from the experiments performed that the ligands coordinate to metal ions in different ways – neutral bidentate or mononegative bidentate – depending on the nature of R. Also, if metal acetates are used instead of metal chlorides, the ligands coordinate in a mononegative bidentate fashion, regardless of the nature of R or the thiosemicarbazone type ligand. The antimicrobial activity of the ligands and of the complexes towards samples of Acinetobacter boumanii, Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa was determined.
Keywords: Thiosemicarbazone complexes; copper complexes; thiosemicarbazones; antimicrobial activity
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MDPI and ACS Style

Rosu, T.; Gulea, A.; Nicolae, A.; Georgescu, R. Complexes of 3dn Metal Ions with Thiosemicarbazones: Synthesis and Antimicrobial Activity. Molecules 2007, 12, 782-796.

AMA Style

Rosu T, Gulea A, Nicolae A, Georgescu R. Complexes of 3dn Metal Ions with Thiosemicarbazones: Synthesis and Antimicrobial Activity. Molecules. 2007; 12(4):782-796.

Chicago/Turabian Style

Rosu, Tudor; Gulea, Aurelian; Nicolae, Anca; Georgescu, Rodica. 2007. "Complexes of 3dn Metal Ions with Thiosemicarbazones: Synthesis and Antimicrobial Activity." Molecules 12, no. 4: 782-796.


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