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Molecules 2007, 12(2), 205-217; doi:10.3390/12020205

A Novel Antioxidant Phenyl Disaccharide from Populus tremula Knotwood

1,* , 2
3,* , 3
1 Department of Chemistry and Biochemistry, University of Agricultural Sciences and Veterinary Medicine; Manastur 3-5, 400372 Cluj, Napoca, Romania 2 Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche 03202, Alicante, Spain 3 Åbo Akademi University, Process Chemistry Centre, Porthansgatan 3, FI-20500 Turku/Åbo, Finland
* Authors to whom correspondence should be addressed.
Received: 8 January 2007 / Revised: 15 February 2007 / Accepted: 18 February 2007 / Published: 19 February 2007
(This article belongs to the Special Issue Phenolics and Polyphenolics)
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The complete characterization of two compounds obtained from the acetoneextract of Populus tremula knotwood has been was achieved using LC-DAD-MS,MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixtureof the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showedthe capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trapperoxyl radicals, as determined by a chemiluminescence method. These new phenyldisaccharides also showed a significant ORAC (oxygen radical absorbance capacity)value, i.e. 11.7 μM TE (Trolox Equivalents).
Keywords: Populus tremula;phenyl disaccharide; coumaroyl glycoside; p-coumaric acid; HPLC-MS/MS; NMR; antioxidant; knotwood Populus tremula; phenyl disaccharide; coumaroyl glycoside; p-coumaric acid; HPLC-MS/MS; NMR; antioxidant; knotwood
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Neacsu, M.; Micol, V.; Pérez-Fons, L.; Willför, S.; Holmbom, B.; Mallavia, R. A Novel Antioxidant Phenyl Disaccharide from Populus tremula Knotwood. Molecules 2007, 12, 205-217.

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