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A Novel Antioxidant Phenyl Disaccharide from Populus tremula Knotwood
Department of Chemistry and Biochemistry, University of Agricultural Sciences and Veterinary Medicine; Manastur 3-5, 400372 Cluj, Napoca, Romania
Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche 03202, Alicante, Spain
Åbo Akademi University, Process Chemistry Centre, Porthansgatan 3, FI-20500 Turku/Åbo, Finland
* Authors to whom correspondence should be addressed.
Received: 8 January 2007; in revised form: 15 February 2007 / Accepted: 18 February 2007 / Published: 19 February 2007
Abstract: The complete characterization of two compounds obtained from the acetoneextract of Populus tremula knotwood has been was achieved using LC-DAD-MS,MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixtureof the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showedthe capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trapperoxyl radicals, as determined by a chemiluminescence method. These new phenyldisaccharides also showed a significant ORAC (oxygen radical absorbance capacity)value, i.e. 11.7 μM TE (Trolox Equivalents).
Keywords: Populus tremula;phenyl disaccharide; coumaroyl glycoside; p-coumaric acid; HPLC-MS/MS; NMR; antioxidant; knotwood
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MDPI and ACS Style
Neacsu, M.; Micol, V.; Pérez-Fons, L.; Willför, S.; Holmbom, B.; Mallavia, R. A Novel Antioxidant Phenyl Disaccharide from Populus tremula Knotwood. Molecules 2007, 12, 205-217.
Neacsu M, Micol V, Pérez-Fons L, Willför S, Holmbom B, Mallavia R. A Novel Antioxidant Phenyl Disaccharide from Populus tremula Knotwood. Molecules. 2007; 12(2):205-217.
Neacsu, Madalina; Micol, Vicente; Pérez-Fons, Laura; Willför, Stefan; Holmbom, Bjarne; Mallavia, Ricardo. 2007. "A Novel Antioxidant Phenyl Disaccharide from Populus tremula Knotwood." Molecules 12, no. 2: 205-217.