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Molecules 2007, 12(2), 205-217; doi:10.3390/12020205

A Novel Antioxidant Phenyl Disaccharide from Populus tremula Knotwood

1,* , 2
3,* , 3
1 Department of Chemistry and Biochemistry, University of Agricultural Sciences and Veterinary Medicine; Manastur 3-5, 400372 Cluj, Napoca, Romania 2 Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche 03202, Alicante, Spain 3 Åbo Akademi University, Process Chemistry Centre, Porthansgatan 3, FI-20500 Turku/Åbo, Finland
* Authors to whom correspondence should be addressed.
Received: 8 January 2007 / Revised: 15 February 2007 / Accepted: 18 February 2007 / Published: 19 February 2007
(This article belongs to the Special Issue Phenolics and Polyphenolics)
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The complete characterization of two compounds obtained from the acetoneextract of Populus tremula knotwood has been was achieved using LC-DAD-MS,MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixtureof the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showedthe capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trapperoxyl radicals, as determined by a chemiluminescence method. These new phenyldisaccharides also showed a significant ORAC (oxygen radical absorbance capacity)value, i.e. 11.7 μM TE (Trolox Equivalents).
Keywords: Populus tremula;phenyl disaccharide; coumaroyl glycoside; p-coumaric acid; HPLC-MS/MS; NMR; antioxidant; knotwood Populus tremula; phenyl disaccharide; coumaroyl glycoside; p-coumaric acid; HPLC-MS/MS; NMR; antioxidant; knotwood
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Neacsu, M.; Micol, V.; Pérez-Fons, L.; Willför, S.; Holmbom, B.; Mallavia, R. A Novel Antioxidant Phenyl Disaccharide from Populus tremula Knotwood. Molecules 2007, 12, 205-217.

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