Molecules 2007, 12(1), 114-129; doi:10.3390/12010114
Article

Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based Serine Protease Mimics

 and * email
Received: 21 December 2006; in revised form: 29 January 2007 / Accepted: 30 January 2007 / Published: 31 January 2007
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The synthesis of nucleosides modified with an extra imidazole, carboxyl and hydroxyl group is described. These nucleosides can be incorporated into an oligonucleotide duplex, thus generating a novel type of serine protease mimic.
Keywords: Nucleoside synthesis; serine protease mimic; DNA scaffold; 2� modification.
PDF Full-text Download PDF Full-Text [158 KB, uploaded 18 June 2014 19:27 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Catry, M.A.; Madder, A. Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based Serine Protease Mimics. Molecules 2007, 12, 114-129.

AMA Style

Catry MA, Madder A. Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based Serine Protease Mimics. Molecules. 2007; 12(1):114-129.

Chicago/Turabian Style

Catry, Mieke A.; Madder, Annemieke. 2007. "Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based Serine Protease Mimics." Molecules 12, no. 1: 114-129.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert