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Molecules 2007, 12(1), 114-129; doi:10.3390/12010114
Article

Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based Serine Protease Mimics

 and *
Received: 21 December 2006; in revised form: 29 January 2007 / Accepted: 30 January 2007 / Published: 31 January 2007
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Abstract: The synthesis of nucleosides modified with an extra imidazole, carboxyl and hydroxyl group is described. These nucleosides can be incorporated into an oligonucleotide duplex, thus generating a novel type of serine protease mimic.
Keywords: Nucleoside synthesis; serine protease mimic; DNA scaffold; 2� modification. Nucleoside synthesis; serine protease mimic; DNA scaffold; 2� modification.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Catry, M.A.; Madder, A. Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based Serine Protease Mimics. Molecules 2007, 12, 114-129.

AMA Style

Catry MA, Madder A. Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based Serine Protease Mimics. Molecules. 2007; 12(1):114-129.

Chicago/Turabian Style

Catry, Mieke A.; Madder, Annemieke. 2007. "Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based Serine Protease Mimics." Molecules 12, no. 1: 114-129.



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