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Molecules 2007, 12(2), 130-138; doi:10.3390/12020130
Article

Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method

1
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 and 2,*
Received: 22 January 2007; in revised form: 31 January 2007 / Accepted: 1 February 2007 / Published: 3 February 2007
(This article belongs to the Special Issue Phenolics and Polyphenolics)
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Abstract: The radical-scavenging activities of the synthetic antioxidants 2-allyl-4-X-phenol (X=NO2, Cl, Br, OCH3, COCH3, CH3, t-(CH3)3, C6H5) and 2,4-dimethoxyphenol, and the natural antioxidants eugenol and isoeugenol, were investigated using differential scanning calorimetry (DSC) by measuring their anti-1,1-diphenyl-2-picrylhydrazyl (DPPH) radical activity and the induction period for polymerization of methyl methacrylate (MMA) initiated by thermal decomposition of 2,2'-azobisisobutyronitrile (AIBN) and benzoyl peroxide (BPO). 2-Allyl-4-methoxyphenol and 2,4-dimethoxy-phenol scavenged not only oxygen-centered radicals (PhCOO.) derived from BPO, but also carbon-centered radicals (R.) derived from the AIBN and DPPH radical much more efficiently, in comparison with eugenol and isoeugenol. 2-Allyl-4-methoxyphenol may be useful for its lower prooxidative activity.
Keywords: Radical-scavenging activity; natural and synthetic methoxyphenols; DPPH; BPO;AIBN; induction method. Radical-scavenging activity; natural and synthetic methoxyphenols; DPPH; BPO; AIBN; induction method.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Kadoma, Y.; Atsumi, T.; Okada, N.; Ishihara, M.; Yokoe, I.; Fujisawa, S. Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method. Molecules 2007, 12, 130-138.

AMA Style

Kadoma Y, Atsumi T, Okada N, Ishihara M, Yokoe I, Fujisawa S. Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method. Molecules. 2007; 12(2):130-138.

Chicago/Turabian Style

Kadoma, Yoshinori; Atsumi, Toshiko; Okada, Norihisa; Ishihara, Mariko; Yokoe, Ichiro; Fujisawa, Seiichiro. 2007. "Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method." Molecules 12, no. 2: 130-138.


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