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Molecules 2006, 11(6), 478-485; doi:10.3390/11060478
Article

Host-Guest Chemistry of Tolbutamide

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Received: 29 April 2006 / Revised: 13 June 2006 / Accepted: 15 June 2006 / Published: 23 June 2006
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Abstract

The molecular recognition features of tolbutamide with four synthetic hosts have been studied by means of NMR titrations, NOESY experiments and Monte Carlo (MC) conformational search. The interaction strength and the most probable structure reveal new insights on the recognition phenomena of this urea derivative in comparison with close related compounds.
Keywords: Molecular Recognition; Monte Carlo conformational search; NMR titrations; tolbutamide. Molecular Recognition; Monte Carlo conformational search; NMR titrations; tolbutamide.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Herranz, F.; Santa María, M.D.; Claramunt, R.M. Host-Guest Chemistry of Tolbutamide. Molecules 2006, 11, 478-485.

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